Molecular Aspect of Annelid Neuroendocrine system
, 2007 Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
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Proenkephalin and risk of developing chronic kidney disease:The Prevention of Renal and Vascular End-stage Disease study [PDF]
, 2018 BACKGROUND: Proenkephalin (pro-ENK) was recently found to be associated with low estimated glomerular filtration rate (eGFR). The association of pro-ENK with urinary albumin excretion (UAE), another marker for chronic kidney disease (CKD), has not been ...
Bakker, Stephan J. L. +7 more
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Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.Analysis of the chemical profile and antiviral potential of Costus arabicus L. extracts. ABSTRACT Widely used in Brazilian folk medicine, Costus arabicus L. (Canarana) is a herbaceous plant with promising pharmacological potential. Here, we profile the molecular composition of extracts from different plant organs and evaluate their in vitro activity ...
Alice Rhelly V. Carvalho +9 more
wiley +1 more source
Linking Metabolomic Diversity to Pharmacological Potency in Anonidium mannii Leaf Extracts
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.This study investigates the metabolomic profile and pharmacological activities of extracts from Anonidium mannii leaves. The extracts were profiled using an integrated LC‐MS/GC‐MS, and evaluated for antimicrobial, antioxidant and cytotoxic activities, providing a basis for future studies and validation in more advanced biological models.
Olusesan Ojo +2 more
wiley +1 more source
Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis. [PDF]
, 2018 Cardiokines play an essential role in maintaining normal cardiac functions and responding to acute myocardial injury. Studies have demonstrated the heart itself is a significant source of C1q/TNF-related protein 9 (CTRP9). However, the biological role of
Feng, Pan +13 more
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Prosocial Behavior as a Stress Moderator: The Physiological and Psychological Components [PDF]
, 2018 Stress is a major part of everyday life for the majority of people, especially college students. Stress has a physiological response and serves an important purpose in the body.
Vannelli, Jessica
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Specific fluorogenic substrates for neprilysin (neutral endopeptidase, EC 3.4.24.11) which are highly resistant to serine- and metalloproteases [PDF]
, 1997 Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
Boileau, G. +4 more
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Evaluation of Analgesic Activity of Newly Synthesized Phthalyl- tyrosyl-glycin Sodium
Iraqi Journal of Pharmaceutical Sciences, 2017 Alteration in the backbone structure of the endogenously released opioid peptides Leu5/Met5 enkephalins may result in compounds having comparable profile of pharmacological activity but with different physicochemical properties and side effects. Phthalyl
Muthanna S. AL-Taee +2 more
doaj +3 more sources
PLoS ONE, 2019 Dipeptidyl amino-peptidase 3 (DPP3) is an aminopeptidase involved in peptide degradation, including hormone peptides as angiotensin II and enkephalins. DPP3 plasma activity increases in septic patients and correlates with mortality risk.
Paul Kaufmann +7 more
doaj +1 more source
Frontiers in Pharmacology, 2012 Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Marion eEberlin +2 more
doaj +1 more source