Results 141 to 150 of about 11,957 (196)
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Canine bile acid enterohepatic circulation
Steroids, 1982The enterohepatic circulation (EHC) of bile acids has been studied in fasting dogs with portacaval shunt maintained in the steady state. In such animals the rate of EHC is proportional to systemic blood bile acid concentration. Bile acid EHC was irregular (20 to 100% variation) when measured at 15 minute or hourly intervals.
W T, Beher +4 more
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THE ENTEROHEPATIC CIRCULATION OF THYROXINE
Journal of Endocrinology, 1972SUMMARY A quantitative investigation was made of the enterohepatic circulation of endogenous thyroxine (T4) in the rat. Control and cold-acclimated rats were maintained on a low iodine diet and water containing 125I-labelled iodide of known specific activity for 4 weeks. Faeces were then collected over a 3-day period.
V A, Galton, B C, Nisula
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Enterohepatic Circulation of Drugs
The Journal of Clinical Pharmacology, 1989Review on the processes of biliary excretion and enterohepatic circulation of drugs and the pharmacokinetic and pharmacodynamic consequences ...
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Cysteinyl leukotrienes undergo enterohepatic circulation
Prostaglandins, Leukotrienes and Medicine, 1986Abstract Enterohepatic circulation is an important mechanism responsible for extension of the biological half-lives of many endogenous compounds and xenobiotics (1). Cysteinyl leukotrienes play an important role in lethal endotoxin action (2) and in tissue trauma (3).
C, Denzlinger +7 more
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Enterohepatic circulation of sulindac and metabolites
Clinical Pharmacology and Therapeutics, 1983Four subjects were studied by continuous intraduodenal sampling to establish the existence and determine the extent of enterohepatic recirculation of sulindac and its sulfide and sulfone metabolites. Sulindac, 200 mg by mouth, was given every 12 hr for 7 days.
C A, Dujovne +5 more
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2020
The term “Enterohepatic circulation” (EHC) refers to the circulation of metabolites from the intestine to the liver and back to the intestine. Since the first use of the term in 1923, understanding of the detailed physiology, microanatomy, and biochemistry, and of interactions between organs and tissues, has grown dramatically.
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The term “Enterohepatic circulation” (EHC) refers to the circulation of metabolites from the intestine to the liver and back to the intestine. Since the first use of the term in 1923, understanding of the detailed physiology, microanatomy, and biochemistry, and of interactions between organs and tissues, has grown dramatically.
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Crohn's disease and the enterohepatic circulation
Medical Hypotheses, 1981Crohn's disease is a chronic inflammatory process which may affect any part of the alimentary tract. This cause is unknown. Overall the distribution of the lesions coincides with that of the enterohepatic circulation. A possible causative agent is a metabolic or ingested substance excreted into the bile in the form of a polar and inactive conjugates ...
H, Nyhlin, M A, Eastwood
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1975
Substances are said to undergo an enterohepatic circulation (EHC) when they are excreted into the bile, pass into the lumen of the intestine, are reabsorbed and then return to the liver via the circulation. Many endogenous and exogenous substances can undergo an EHC.
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Substances are said to undergo an enterohepatic circulation (EHC) when they are excreted into the bile, pass into the lumen of the intestine, are reabsorbed and then return to the liver via the circulation. Many endogenous and exogenous substances can undergo an EHC.
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1983
The principal components of bile are the conjugated bile acids, cholesterol, and phospholipid, but in addition to these major components there is a vast array of minor components. Some of these are waste products of metabolism excreted by secretion in the bile, for example, bilirubin and the bile pigments.
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The principal components of bile are the conjugated bile acids, cholesterol, and phospholipid, but in addition to these major components there is a vast array of minor components. Some of these are waste products of metabolism excreted by secretion in the bile, for example, bilirubin and the bile pigments.
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Enterohepatic circulation of N-acetyl-leukotriene E4
Prostaglandins, 1987N-Acetyl-leukotriene E4, the end product of leukotriene C4 metabolism in the mercapturic acid pathway, was rapidly eliminated from the blood circulation into the bile of rats. Part of the N-acetyl-leukotriene E4 secreted from bile into the intestine underwent enterohepatic circulation.
A, Guhlmann, W, Hagmann, D, Keppler
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