Results 161 to 170 of about 603,469 (215)

Bile acids and bile acid modification in health and disease: from novel modifications to therapeutic interventions. [PDF]

Front Endocrinol (Lausanne)
Yu C, Ye X, Zhao H, Qian S, Xie F, Liu Q.   +5 more
europepmc   +1 more source

Bile acid dysregulation in Fontan circulation: A Parallel to hyperglycemia in diabetes? [PDF]

Ann Pediatr Cardiol
Shah AH.
europepmc   +1 more source

Antibiotic-induced gut microbiota dysbiosis and bile acid metabolism: implications for intestinal health, immune regulation, and disease susceptibility. [PDF]

Front Microbiol
AlRamadneh TN, Rizaev J, Hanumanthayya M, Al-Hussein MA, Mutee AF, Buriev M, Jumaniyazova N, Shefali.   +7 more
europepmc   +1 more source

Enterohepatic Circulation

Clinical Pharmacokinetics, 2002
Enterohepatic recycling occurs by biliary excretion and intestinal reabsorption of a solute, sometimes with hepatic conjugation and intestinal deconjugation. Cycling is often associated with multiple peaks and a longer apparent half-life in a plasma concentration-time profile.
Roberts, M. S., Magnusson, B. M., Burczynski, F. J., Weiss, M.   +3 more
openaire   +6 more sources

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A method for investigation of enterohepatic circulation

Naunyn-Schmiedeberg's Archives of Pharmacology, 1972
A method is described for simultaneous determination of a drug and its metabolites in blood and bile of rats with intact enterohepatic circulation. The comparison with the respective data obtained in biliary fistula animals allows a statement on enterohepatic circulation of the drug, if the bile flow is identical in both groups.
U Abshagen
exaly   +3 more sources

Evidence for an enterohepatic circulation of ochratoxin A in mice

Toxicology, 1988
The distribution and elimination of [3H]ochratoxin A (OTA) from stomach content and tissue, intestine content and tissue, liver, bile, serum and urine of Swiss male mice which had received a single low dose of OTA by intubation was followed as a function of time.
E E Creppy, G Dirheimer, Guy Dirheimer
exaly   +3 more sources

Effect of Enterohepatic Circulation on the Accumulation of Per- and Polyfluoroalkyl Substances: Evidence from Experimental and Computational Studies

Environmental Science & Technology, 2022
The pharmacokinetic characteristics of per- and polyfluoroalkyl substances (PFAS) affect their distribution and bioaccumulation in biological systems. The enterohepatic circulation leads to reabsorption of certain chemicals from bile back into blood and ...
Zhen Zhou, Yong Liang, Thanh Wang
exaly   +2 more sources

Metabolic consequences of ileal interruption of the enterohepatic circulation of bile acids [PDF]

American Journal of Physiology - Renal Physiology, 2020
The enterohepatic circulation of bile acids comprises a tightly regulated process of hepatic bile acid secretion, intestinal reabsorption and transport back to the liver.
Johan Jonker, Ivo Pieter van de Peppel, Henkjan J Verkade   +2 more
exaly   +3 more sources

Regulating the absorption and excretion of perfluorooctane sulfonate and its alternatives through influencing enterohepatic circulation

Science of the Total Environment
Data source: Supplementary data, https://doi.org/10.1016/j.scitotenv.2024.173161Enterohepatic circulation has been reported to play a significant role in the bioaccumulation of PFASs.
Albert Juhasz, Xinyi Cui
exaly   +2 more sources

Enterohepatic circulation in the rat

Gastroenterology, 1985
Several compounds, in particular bile acids, undergo enterohepatic circulation (EHC). Limited data are available on the pathophysiologic aspects of this circulation. In the present study we describe a surgical technique in rats that allows a long-term, reversible interruption of the EHC and monitoring of peripheral blood levels without direct surgical ...
KUIPERS, F, HAVINGA, R, BOSSCHIETER, H, TOOROP, GP, HINDRIKS, FR, VONK, RJ   +5 more
openaire   +3 more sources