Results 171 to 180 of about 603,469 (215)
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ENTEROHEPATIC CIRCULATION OF OESTROGENS
Obstetrical & Gynecological Survey, 1944Abstract Evidence that the liver destroys the activity of oestrogens has been strongly presented in a long list of publications and there appears to be no serious dissenting opinion [Cantarow, Rakoff, Paschkis, Hansen & Walkling, 1943].
F E, EMERY, H E, JOYCE
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Enterohepatic Circulation of Urobilinogen
Nature, 1964THE bacteria of the large bowel reduce bile bilirubin to colourless, Ehrlich-positive chromogens, collectively termed urobilinogen1. It has been stated that urobilinogen is partly re-absorbed from the colon, and afterwards re-excreted in the bile, and, to a lesser degree, in the urine2.
R, LESTER, R, SCHMID
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THE ENTEROHEPATIC CIRCULATION OF THYROXINE
Journal of Endocrinology, 1972SUMMARY A quantitative investigation was made of the enterohepatic circulation of endogenous thyroxine (T4) in the rat. Control and cold-acclimated rats were maintained on a low iodine diet and water containing 125I-labelled iodide of known specific activity for 4 weeks. Faeces were then collected over a 3-day period.
V A, Galton, B C, Nisula
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Enterohepatic circulation of sulindac and metabolites
Clinical Pharmacology and Therapeutics, 1983Four subjects were studied by continuous intraduodenal sampling to establish the existence and determine the extent of enterohepatic recirculation of sulindac and its sulfide and sulfone metabolites. Sulindac, 200 mg by mouth, was given every 12 hr for 7 days.
C A, Dujovne +5 more
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Enterohepatic Circulation of Drugs
The Journal of Clinical Pharmacology, 1989Review on the processes of biliary excretion and enterohepatic circulation of drugs and the pharmacokinetic and pharmacodynamic consequences ...
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Crohn's disease and the enterohepatic circulation
Medical Hypotheses, 1981Crohn's disease is a chronic inflammatory process which may affect any part of the alimentary tract. This cause is unknown. Overall the distribution of the lesions coincides with that of the enterohepatic circulation. A possible causative agent is a metabolic or ingested substance excreted into the bile in the form of a polar and inactive conjugates ...
H, Nyhlin, M A, Eastwood
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2020
The term “Enterohepatic circulation” (EHC) refers to the circulation of metabolites from the intestine to the liver and back to the intestine. Since the first use of the term in 1923, understanding of the detailed physiology, microanatomy, and biochemistry, and of interactions between organs and tissues, has grown dramatically.
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The term “Enterohepatic circulation” (EHC) refers to the circulation of metabolites from the intestine to the liver and back to the intestine. Since the first use of the term in 1923, understanding of the detailed physiology, microanatomy, and biochemistry, and of interactions between organs and tissues, has grown dramatically.
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Modeling Enterohepatic Circulation
Current Pharmacology Reports, 2017The objective of the current analysis is to review the anatomy and physiology of the enterohepatic circulation (EHC); describe how those intricacies affect drug concentration profiles; present various pharmacokinetic models used in the literature to describe EHC concentration-time data; and provide a categorization of these models based on common ...
Malek Okour, Richard C. Brundage
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Enterohepatic Circulation of Tetracycline in Rats
Journal of Pharmaceutical Sciences, 1975The absorption of tetracycline hydrochloride excreted in the bile of rats was evaluated using the insitu intestinal preparation. For comparative purposes, the absorption of the drug from an aqueous solution having the same pH as that of the bile was also determined.
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The enterohepatic circulation in glutethimide intoxication
Clinical Pharmacology & Therapeutics, 1970The role of the enterohepatic circulation in glutethimide (Doriden) metabolism and toxicity was investigated in patients and dogs undergoing biliary drailwge. Bile collected after the oral or parenteral administration of glutethimide contained insignificant quantities of active and unmetabolized drug. Oral administration of glutethimide both before and
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