Results 41 to 50 of about 64,082 (215)

Computational Approach for Predicting Common Epitopes in the VP1 Structural Protein of Enterovirus Serotypes EV-D68, EV-D70, and EV-A71

Journal of Pure and Applied Microbiology, 2021
The three human Enterovirus serotypes D-68, D-70, and A-71, are common pathogens that are transmitted by fecal-oral and aerosol routes. These positive RNA viruses were known to exhibit high levels of genetic diversity and variability.
Rihabe Boussettine, Yassine Kasmi, Najwa Hassou, Hlima Bessi, Moulay Mustapha Ennaji   +4 more
doaj   +1 more source

CORRELATION BETWEEN ENROVIRUS INFECTION AND ACUTE STROKE ON THE GROUND OF VIROLOGICAL, MOLECULAR GENETIC AND SEROLOGICAL METHODS OF DIAGNOSIS

Медична наука України, 2018
Relevance. Numerous virological studies prove the importance of enteroviruses in human somatic pathology. However, the etiopathogenetic role of enterovirus infection in patients with acute cerebrovascular disorder (GVMK) is not sufficiently highlighted.
N.G. Andriushkova, N.S. Turchina, V.V. Melnуk, L.V. Dolinchuk, V.A. Poniatovskyi, V.P. Shyrobokov   +5 more
doaj   +1 more source

Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT Although the genus Enterovirus contains many important human pathogens, there is no licensed drug for either the treatment or the prophylaxis of enterovirus infections. We report that fluoxetine (Prozac)—a selective serotonin reuptake inhibitor—inhibits the replication of human enterovirus B (HEV ...
Ulferts, R., van der Linden, L., Thibaut, H.J., Lanke, K.H.W., Leyssen, P., Coutard, B., De Palma, A.M., Canard, B., Neyts, J., van Kuppeveld, F.J.M., van Kuppeveld, F.J.M.   +10 more
openaire   +5 more sources

High frequency of enterovirus serotype circulation in a densely populated area of India

Journal of Infection in Developing Countries, 2013
Introduction: In the state of Uttar Pradesh in India, enteroviruses are a significant cause of infection presenting in endemic or epidemic forms. The present study aimed to use molecular methods to identify enterovirus serotypes in clinical specimens to
Arvind Kumar, Deepti Shukla, Shalini Srivastava, Mohammad Z Idris, Tapan N Dhole   +4 more
doaj   +1 more source

First evidence of enterovirus A71 and echovirus 30 in Uruguay and genetic relationship with strains circulating in the South American region.

PLoS ONE, 2021
Human enteroviruses (EVs) comprise more than 100 types of coxsackievirus, echovirus, poliovirus and numbered enteroviruses, which are mainly transmitted by the faecal-oral route leading to diverse diseases such as aseptic meningitis, encephalitis, and ...
Andrés Lizasoain, Daiana Mir, Matías Salvo, Viviana Bortagaray, Gisela Masachessi, Adrián Farías, Nélida Rodríguez-Osorio, Silvia Nates, Matías Victoria, Rodney Colina   +9 more
doaj   +1 more source

SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication. [PDF]

, 2016
Accumulating evidence suggests that viruses hijack cellular proteins to circumvent the host immune system. Ubiquitination and SUMOylation are extensively studied posttranslational modifications (PTMs) that play critical roles in diverse biological ...
Gong, P, Hu, Q, Ke, X, Liu, Y, Meng, J, Shu, B, Wang, H, Zhang, Y, Zheng, C, Zheng, Z   +9 more
core   +1 more source

Enterovirus serotypes in patients with central nervous system and respiratory infections in Viet Nam 1997–2010

Virology Journal, 2018
Background Enteroviruses are the most common causative agents of human illness. Enteroviruses have been associated with regional and global epidemics, recently, including with severe disease (Enterovirus A71 and D68), and are of interest as emerging ...
Nguyen Thi Thuy Chinh B’Krong, Ngo Ngoc Quang Minh, Phan Tu Qui, Tran Thi Hong Chau, Ho Dang Trung Nghia, Lien Anh Ha Do, Nguyen Ngoc Nhung, Nguyen Van Vinh Chau, Guy Thwaites, Le Van Tan, H. Rogier van Doorn, Tran Tan Thanh   +11 more
doaj   +1 more source

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E, Mangale, Vrushali, Marro, Brett S, Plaisted, Warren C, Walsh, Craig M   +4 more
core   +1 more source

The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]

, 2014
Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J., Evans, David J., Simmonds, Peter, Witteveldt, Jeroen   +3 more
core   +2 more sources

Streptococcus pneumoniae nasal carriage patterns with and without common respiratory virus detections in households in Seattle, WA, USA before and during the COVID-19 pandemic

Frontiers in Pediatrics, 2023
BackgroundRespiratory viruses might influence Streptococcus pneumoniae nasal carriage and subsequent disease risk. We estimated the association between common respiratory viruses and semiquantitative S.
Julia C. Bennett, Julia C. Bennett, Anne Emanuels, Jessica Heimonen, Jessica O'Hanlon, James P. Hughes, Peter D. Han, Peter D. Han, Eric J. Chow, Eric J. Chow, Eric J. Chow, Constance E. Ogokeh, Constance E. Ogokeh, Melissa A. Rolfes, Christine M. Lockwood, Christine M. Lockwood, Brian Pfau, Brian Pfau, Timothy M. Uyeki, Jay Shendure, Jay Shendure, Samara Hoag, Kairsten Fay, Jover Lee, Thomas R. Sibley, Julia H. Rogers, Julia H. Rogers, Lea M. Starita, Lea M. Starita, Janet A. Englund, Helen Y. Chu   +30 more
doaj   +1 more source