Results 41 to 50 of about 1,391 (151)

Subtype-Based Analysis of Cell-in-Cell Structures in Esophageal Squamous Cell Carcinoma

Frontiers in Oncology, 2021
Cell-in-cell (CIC) structures are defined as the special structures with one or more cells enclosed inside another one. Increasing data indicated that CIC structures were functional surrogates of complicated cell behaviors and prognosis predictor in ...
Yuqi Wang, Yuqi Wang, Zubiao Niu, Lulin Zhou, Lulin Zhou, Yongan Zhou, Qunfeng Ma, Yichao Zhu, Mengzhe Liu, Yinan Shi, Yinan Shi, Yanhong Tai, Qiuju Shao, Jianlin Ge, Jilei Hua, Lihua Gao, Hongyan Huang, Hong Jiang, Qiang Sun   +18 more
doaj   +1 more source

The Impact of Polyploid Giant Cancer Cells: The Root of Stress Resilience. [PDF]

Cancer Sci
Among the diverse characteristics of polyploid giant cancer cells (PGCCs) observed in various contexts, stress resilience is one of their key features, enabling survival and adaptation under harsh conditions. This review discusses the unique stress tolerance mechanisms of PGCCs and their implications for cancer progression, therapy resistance, and ...
Ogawa Y, Fisher L, Matsumoto T.
europepmc   +2 more sources

T-cell entosis in the liver: catching escaping t-cells and The expression of e3 ubiquitin ligases in t-cells [PDF]

, 2013
Entosis describes a form of emperipolesis, where one cell invades a host cell. Emperipolesis can result in death, division or release of the internalised cell.
Purswani, Sudha
core   +6 more sources

Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy

eLife, 2022
Despite the remarkable successes of cancer immunotherapies, the majority of patients will experience only partial response followed by relapse of resistant tumors.
Amit Gutwillig, Nadine Santana-Magal, Leen Farhat-Younis, Diana Rasoulouniriana, Asaf Madi, Chen Luxenburg, Jonathan Cohen, Krishnanand Padmanabhan, Noam Shomron, Guy Shapira, Annette Gleiberman, Roma Parikh, Carmit Levy, Meora Feinmesser, Dov Hershkovitz, Valentina Zemser-Werner, Oran Zlotnik, Sanne Kroon, Wolf-Dietrich Hardt, Reno Debets, Nathan Edward Reticker-Flynn, Peleg Rider, Yaron Carmi   +22 more
doaj   +1 more source

Mechanical Ring Interfaces between Adherens Junction and Contractile Actomyosin to Coordinate Entotic Cell-in-Cell Formation

Cell Reports, 2020
Summary: Entosis is a cell-in-cell (CIC)-mediated death program. Contractile actomyosin (CA) and the adherens junction (AJ) are two core elements essential for entotic CIC formation, but the molecular structures interfacing them remain poorly understood.
Manna Wang, Zubiao Niu, Hongquan Qin, Banzhan Ruan, You Zheng, Xiangkai Ning, Songzhi Gu, Lihua Gao, Zhaolie Chen, Xiaoning Wang, Hongyan Huang, Li Ma, Qiang Sun   +12 more
doaj   +1 more source

Cell-in-Cell Structures in the Liver: A Tale of Four E’s

Frontiers in Immunology, 2020
The liver is our largest internal organ and it plays major roles in drug detoxification and immunity, where the ingestion of extracellular material through phagocytosis is a critical pathway. Phagocytosis is the deliberate endocytosis of large particles,
Scott P. Davies, Lauren V. Terry, Alex L. Wilkinson, Zania Stamataki, Zania Stamataki   +4 more
doaj   +1 more source

Types of Cell Death from a Molecular Perspective

Biology, 2023
The former conventional belief was that cell death resulted from either apoptosis or necrosis; however, in recent years, different pathways through which a cell can undergo cell death have been discovered. Various types of cell death are distinguished by
Fatemeh Hajibabaie, Navid Abedpoor, Parisa Mohamadynejad   +2 more
doaj   +1 more source

Emperipolesis, entosis and cell cannibalism: Demystifying the cloud

Journal of Oral and Maxillofacial Pathology, 2017
There are intense published data in literature related to cell engulfment phenomena such as emperipolesis, entosis and cell cannibalism. All these are closely related phenomena with a very fine line of differences. Its correct identification has a significant diagnostic and prognostic value.
Gupta, Nidhi, Jadhav, Kiran, Shah, Vandana   +2 more
openaire   +3 more sources

Cell-in-Cell Phenomenon and Its Relationship With Tumor Microenvironment and Tumor Progression: A Review

Frontiers in Cell and Developmental Biology, 2019
The term cell-in-cell, morphologically, refers to the presence of one cell within another. This phenomenon can occur in tumors but also among non-tumor cells.
Xinlong Wang, Xinlong Wang, Yilong Li, Yilong Li, Jiating Li, Jiating Li, Le Li, Le Li, Hong Zhu, Hua Chen, Hua Chen, Rui Kong, Rui Kong, Gang Wang, Gang Wang, Yongwei Wang, Yongwei Wang, Jisheng Hu, Jisheng Hu, Bei Sun, Bei Sun   +20 more
doaj   +1 more source

Michael Overholtzer: Answering existential questions on entosis [PDF]

Journal of Cell Biology, 2011
Overholtzer is working to understand how and why tumor cells invade one another.
openaire   +1 more source