Results 1 to 10 of about 5,373,729 (260)

Metabolomic Analysis of Environmental Biomarkers Reveals Markers of Mate Preference in Female Giant Pandas. [PDF]

Animals (Basel)
The giant panda (Ailuropoda melanoleuca) is a vulnerable animal in China, and it is crucial to improve the reproduction efficiency of the giant panda. Mate preference is an important part of natural mating.
Feng Y, Ke J, Huang X, Wang M, Li M, Lan J, Wu K, Wang L.   +7 more
europepmc   +2 more sources

Evaluation of sediment contamination by urban sewage in a stretch of Capibaribe River, Pernambuco, Brazil [PDF]

Química Nova, 2023
Anthropic activities are responsible for the increase in environmental contamination, especially in aquatic systems, demanding studies to assess and monitor contamination levels in different water bodies.
Bruna Ramos de Souza Gomes, Rebeca dos Santos França, Alex Souza Moraes, Giovana Anceski Bataglion, Jandyson Machado Santos   +4 more
doaj   +1 more source

Aflatoxin levels and prevalence of TP53 aflatoxin-mutations in hepatocellular carcinomas in Mexico

Salud Pública de México, 2022
Objective. To determine the exposure to aflatoxin B1 (AFB1) in southern Mexico and the presence of the aflatoxin signature mutation in hepatocellular carcinoma (HCC) tissue from patients from a cancer referral center. Materials and methods.
Leonardo S Lino-Silva, Martín Lajous, Marion Brochier, Luis Santiago-Ruiz, Javier Melchor-Ruan, Yi Xie, Mingyi Wang, Dongjing Wu, Herbert Higson, Kristine Jones, Martin Romero-Martínez, Salvador Villalpando, Alejandro Mohar, Joshua W Smith, Christian S Alvarez, Katherine A McGlynn, Michael Dean, John Groopman   +17 more
doaj   +1 more source

Mitochondrial Dysfunction as a Hallmark of Environmental Injury

Cells, 2021
Environmental factors including diet, sedentary lifestyle and exposure to pollutants largely influence human health throughout life. Cellular and molecular events triggered by an exposure to environmental pollutants are extremely variable and depend on ...
Carolina Duarte-Hospital, Arnaud Tête, François Brial, Louise Benoit, Meriem Koual, Céline Tomkiewicz, Min Ji Kim, Etienne B. Blanc, Xavier Coumoul, Sylvie Bortoli   +9 more
doaj   +1 more source

hTERT DNA Methylation Analysis Identifies a Biomarker for Retinoic Acid-Induced hTERT Repression in Breast Cancer Cell Lines

Biomedicines, 2022
Telomerase reactivation is responsible for telomere preservation in about 90% of cancers, providing cancer cells an indefinite proliferating potential.
Eric Nguyen, Andréa Richerolle, Júlia Sánchez-Bellver, Jacqueline Varennes, Evelyne Ségal-Bendirdjian   +4 more
doaj   +1 more source

Spi1 R235C point mutation confers hypersensitivity to radiation-induced acute myeloid leukemia in mice

iScience, 2023
Summary: Ionizing radiation (IR) is a risk factor for acute myeloid leukemia (rAML). Murine rAMLs feature both hemizygous chromosome 2 deletions (Del2) and point mutations (R235) within the hematopoietic regulatory gene Spi1.
Natalie Brown, Rosemary Finnon, Paul Finnon, Roisin McCarron, Lourdes Cruz-Garcia, Grainne O’Brien, Eleanor Herbert, Cheryl L. Scudamore, Edouard Morel, Christophe Badie   +9 more
doaj   +1 more source

Assessing the Impacts of Preanalytical Field Sampling Challenges on the Reliability of Serum Aflatoxin B1-Lysine Measurements by Use of LC-MS/MS

Toxins, 2022
Aflatoxin exposure is endemic in developing countries with warm, humid climates that promote toxigenic mold growth on crops and foodstuffs. Estimating human aflatoxin exposure is key to identifying and abating contamination sources.
Nicholas C. Zitomer, Michael E. Rybak, Maya R. Sternberg   +2 more
doaj   +1 more source

The biogenesis and biological function of PIWI-interacting RNA in cancer

Journal of Hematology & Oncology, 2021
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant levels of small ncRNAs are commonly found in precancerous lesions and cancer.
Silu Chen, Shuai Ben, Junyi Xin, Shuwei Li, Rui Zheng, Hao Wang, Lulu Fan, Mulong Du, Zhengdong Zhang, Meilin Wang   +9 more
doaj   +1 more source

Oxidative Stress and X-ray Exposure Levels-Dependent Survival and Metabolic Changes in Murine HSPCs

Antioxidants, 2021
Haematopoietic bone marrow cells are amongst the most sensitive to ionizing radiation (IR), initially resulting in cell death or genotoxicity that may later lead to leukaemia development, most frequently Acute Myeloid Leukaemia (AML).
Melis Karabulutoglu, Rosemary Finnon, Lourdes Cruz-Garcia, Mark A. Hill, Christophe Badie   +4 more
doaj   +1 more source

LncRNA BCCE4 Genetically Enhances the PD‐L1/PD‐1 Interaction in Smoking‐Related Bladder Cancer by Modulating miR‐328‐3p‐USP18 Signaling

Advanced Science, 2023
Identification of cancer‐associated variants, especially those in functional regions of long noncoding RNAs (lncRNAs), has become an essential task in tumor etiology.
Rui Zheng, Fang Gao, Zhenguang Mao, Yanping Xiao, Lin Yuan, Zhengkai Huang, Qiang Lv, Chao Qin, Mulong Du, Zhengdong Zhang, Meilin Wang   +10 more
doaj   +1 more source