Results 51 to 60 of about 51,921 (307)

Targeting eosinophils: severe asthma and beyond

Drugs in Context, 2019
Recent research in the field of bronchial asthma has mainly focused on eosinophilic disease phenotype. Several trials proved the efficacy and safety profile of eosinophils and interleukin (IL)-5 targeting molecules, currently approved for severe asthma ...
Marco, Francesco, Lucia, Gianenrico
doaj   +1 more source

Successful treatment with dupilumab for mucus plugs in severe asthma

Respirology Case Reports, 2023
A 29‐year‐old man presented to our hospital with severe eosinophilic asthma. He needed a short OCS burst for exacerbation of asthma once every 1 or 2 months, although he used a high dose of inhaled corticosteroids and a long‐acting beta‐2 agonists. Chest
Moriyasu Anai, Chieko Yoshida, Hiroki Izumi, Kei Muramoto, Koichi Saruwatari, Yusuke Tomita, Hidenori Ichiyasu, Takuro Sakagami   +7 more
doaj   +1 more source

Eosinophil Apoptosis and Clearance in Asthma [PDF]

, 2013
Peer reviewedPublisher ...
Bickham U.R., Duval E., Fadok V.A., Fadok V.A., Gaipl U.S., Hart S.P., Luttmann W., Meagher L.C., Schwartz B.R., Walsh G.M.   +9 more
core   +3 more sources

Eosinophil trafficking in asthma [PDF]

Clinical Medicine, 2001
Asthma is characterised by a 50-fold increase in the number of eosinophils relative to neutrophils in the bronchial mucosa. This is the result of the cumulative and sequential effects of several, approximately fourfold, increases in selective eosinophil versus neutrophil migration occurring at a number of stages in the life cycle of the eosinophil ...
openaire   +2 more sources

Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]

, 2019
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna), Shadrin, O. (Oleg)   +1 more
core   +3 more sources

Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults [PDF]

, 2009
BackgroundThe measurement of severity and control of asthma in both children and adults can be based on subjective or objective measures. It has been advocated that fractional exhaled nitric oxide (FeNO) can be used to monitor airway inflammation as it ...
American Thoracic Society, Douwes, Dupont, Franklin, Franklin, Fritsch, Gelb, Griese, Higgins, Jatakanon, Jatakanon, Jones, Jones, Jongste, Kharitonov, Kharitonov, Lim, Malmberg, Malmberg, Nordvall, Petsky, Pijnenburg, Pijnenburg, Prasad, Sanders, Shaw, Smith, Strunk, Szefler, Szefler, Zacharasiewicz   +30 more
core   +4 more sources

PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study

Allergy, Asthma & Clinical Immunology, 2023
Background The prevalence of eosinophilic asthma in Lebanon, one of the most severe phenotypes among severe asthma, is not known. This study aimed at determining the prevalence of the eosinophilic phenotype defined as an eosinophil count ≥ 300 cells/mm3 ...
Wajdi Abi Saleh, Zuhair Alameh, Zeina Aoun Bacha, Joudy Bahous, Pierre Bou Khalil, Zahia Chahine, Hassan Chami, Georges Dabar, Hassan Dheiny, Alfred Dib, Dany farhat, Carla Irani, Georges Juvelekian, Nadim Kanj, Bassam Mansour, Moussa Riachi, Mirna Waked, Mohamad Yassine, Carole Youakim, Salah Zeinedine, Fares Zaitoun   +20 more
doaj   +1 more source

Personalized and Precision Medicine in Asthma and Eosinophilic Esophagitis: The Role of T2 Target Therapy

Pharmaceutics, 2023
The role of type 2 inflammation has been progressively associated with many diseases, including severe asthma, atopic dermatitis, nasal polyposis, eosinophilic granulomatosis with polyangiitis, and, recently, eosinophilic esophagitis.
Diego Bagnasco, Edoardo Vincenzo Savarino, Mona-Rita Yacoub, Fulvio Braido, Maria Giulia Candeliere, Edoardo Giannini, Giovanni Passalacqua, Elisa Marabotto   +7 more
doaj   +1 more source

Chronic rhinosinusitis with nasal polyps in older adults : clinical presentation, pathophysiology, and comorbidity

, 2019
Purpose of Review Chronic rhinosinusitis and nasal polyps (CRSwNP) is a common condition that significantly affects patients' life. This work aims to provide an up-to-date overview of CRSwNP in older adults, focusing on its aging-related clinical ...
Bachert, Claus, Lee, Ji-Hyang, Song, Woo-Jung, Won, Ha-Kyeong   +3 more
core   +2 more sources

The identification of eosinophilic gastroenteritis in prednisone-dependent eosinophilic bronchitis and asthma

Allergy, Asthma & Clinical Immunology, 2011
This case reports the unique association of eosinophilic gastrointestinal disease with eosinophilic bronchitis, asthma and chronic rhinosinusitis and some features of lymphocytic hypereosinophilic syndrome, describes a diagnostic protocol for patients ...
Nair Parameswaran, Ochkur Sergei I, Protheroe Cheryl, Simms Elizabeth, Lee Nancy A, Lee James J   +5 more
doaj   +1 more source