Results 81 to 90 of about 276,902 (250)
Clinical usefulness of mepolizumab in severe eosinophilic asthma
, 2016 Francesco Menzella, Mirco Lusuardi, Gloria Montanari, Carla Galeone, Nicola Facciolongo, Luigi ZucchiDepartment of Cardio-Thoracic-Vascular and Intensive Care Medicine, Pneumology Unit, IRCCS – Arcispedale Santa Maria Nuova, Reggio Emilia ...Galeone C, Montanari G, Menzella F, Facciolongo N, Lusuardi M, Zucchi L +5 morecore System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis
iMetaMed, EarlyView.This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...Bixing Fang, Fei Pan, Yachun Li, Yimeng Wang, Ze Wang, Zhiheng Huang, Ming Chen, Yun Li, Mengli Huang, Cheng Guo, Chubo Xie, Lina Dong, Yadong Gao, Zhuohang Yu +13 morewiley +1 more sourceOld disease, new twist
Journal of Hospital Medicine, EarlyView.Abstract
An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield +4 morewiley +1 more sourceChronic conditions associated with paediatric onset inflammatory bowel diseases: A population‐based study
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objective
Several conditions are associated with inflammatory bowel disease (IBD), including immune‐mediated inflammatory diseases (IMIDs), extraintestinal manifestations (EIMs), and psychiatric disorders. This study aimed to describe at population‐level the comorbidities and their relative burden in paediatric‐onset IBD (pIBD).Nicolas Richard, Ariane Leroyer, Hélène Sarter, Claire Dupont, Dominique Turck, Valérie Bertrand, Pauline Wils, Corinne Gower‐Rousseau, Guillaume Savoye, Nathalie Guillon, Delphine Ley, Mathurin Fumery, EPIMAD Study Group, R. Al Hameedi, M. Al Khatib, S. Al Turk, E. Agoute, J.M. Andre, M. Antonietti, A. Aouakli, A. Armand, L. Armengol‐Debeir, I. Aroichane, F. Assi, J.P. Aubet, E. Auxenfants, A. Avram, F. Ayafi‐Ramelot, K. Azzouzi, D. Bankovski, B. Barbry, N. Bardoux, P. Baron, A. Baudet, P. Bayart, B. Bazin, A. Bebahani, J.P. Becqwort, S. Bellati, V. Benet, H. Benali, C. Benard, C. Benguigui, E. Ben Soussan, A. Bental, I. Berkelmans, J. Bernet, K. Bernou, C. Bernou‐Dron, P. Bertot, N. Bertiaux‐Vandaële, V. Bertrand, E. Billoud, N. Biron, B. Bismuth, M. Bleuet, F. Blondel, V. Blondin, M. Bobula, P. Bohon, V. Bondjemah, E. Boniface, D. Bonkovski, P. Bonnière, E. Bonvarlet, P. Bonvarlet, A. Boruchowicz, R. Bostvironnois, M. Boualit, A. Bouazza, B. Bouche, C. Boudaillez, C. Bourgeaux, M. Bourgeois, A. Bourguet, A. Bourienne, H. Boutaleb, A. Bouthors, J. Branche, G. Bray, F. Brazier, P. Breban, M. Bridenne, H. Brihier, L. Bril, V. Brung‐Lefebvre, P. Bulois, P. Burgiere, J. Butel, J.Y. Canva, V. Canva‐Delcambre, J.P. Capron, F. Cardot, S. Carette, P. Carpentier, E. Cartier, J.F. Cassar, M. Cassagnou, J.F. Castex, P. Catala, S. Cattan, S. Catteau, B. Caujolle, G. Cayron, C. Chandelier, M. Chantre, J. Charles, T. Charneau, M. Chavance‐Thelu, A. Cheny, D. Chirita, A. Choteau, J.F. Claerbout, P.Y. Clergue, H. Coevoet, G. Cohen, R. Collet, M. Colin, J.F. Colombel, S. Coopman, L. Cordiez, J. Corvisart, A. Cortot, F. Couttenier, J.F. Crinquette, V. Crombe, I. Dadamessi, H. Daoudi, V. Dapvril, T. Davion, S. Dautreme, J. Debas, S. Decoster, N. Degrave, F. Dehont, C. Delatre, R. Delcenserie, D. Delesalle, O. Delette, T. Delgrange, L. Delhoustal, J.S. Delmotte, S. Demmane, G. Deregnaucourt, P. Descombes, J.P. Desechalliers, P. Desmet, P. Desreumaux, G. Desseaux, P. Desurmont, A. Devienne, E. Devouge, M. Devred, A. Devroux, A. Dewailly, S. Dharancy, A. Di Fiore, D. Djedir, R. Djedir, W. Doleh, Ml. Dreher‐Duwat, R. Dubois, C. Duburque, P. Ducatillon, J. Duclay, B. Ducrocq, F. Ducrot, P. Ducrotte, A. Dufilho, C. Duhamel, D. Dujardin, C. Dumant‐Forest, J.L. Dupas, F. Dupont, Y. Duranton, A. Duriez, N. Duveau, K. El Achkar, M. El Farisi, C. Elie, M.C. Elie‐Legrand, A. Elkhaki, M. Eoche, E. Essmaeel, D. Evrard, J.P. Evrard, A. Fatome, B. Filoche, L. Finet, M. Flahaut, C. Flamme, D. Foissey, P. Fournier, Mc. Foutrein‐ Comes, P. Foutrein, D. Fremond, T. Frere, M. Fumery, P. Gallais, C. Gamblin, S. Ganga, R. Gerard, G. Geslin, Y. Gheyssens, N. Ghossini, S. Ghrib, T Gilbert, B. Gillet, D. Godart, P. Godard, J.M. Godchaux, R. Godchaux, G. Goegebeur, O. Goria, F. Gottrand, P. Gower, B. Grandmaison, M. Groux, C. Guedon, L. Guerbeau, M. Gueroult‐Dero, J.F. Guillard, L. Guillem, F. Guillemot, D. Guimberd, B. Haddouche, S. Hakim, D. Hanon, V. Hautefeuille, P. Heckestweiller, G. Hecquet, J.P. Hedde, H. Hellal, P.E. Henneresse, B. Heyman, M. Heraud, S. Herve, P. Hochain, L. Houssin‐Bailly, P. Houcke, B. Huguenin, S. Iobagiu, S. Istanboli, A. Ivanovic, I. Iwanicki‐Caron, E. Janicki, M. Jarry, J. Jeu, Jp. Joly, C. Jonas, A. Jouvenet, F. Katherin, A. Kerleveo, A. Khachfe, A. Kiriakos, J. Kiriakos, O. Klein, M. Kohut, R. Kornhauser, D. Koutsomanis, Je. Laberenne, E. Lacotte, G. Laffineur, M. Lagarde, A. Lalanne, A. Lalieu, P. Lannoy, J. Lapchin, M. Laprand, D. Laude, R. Leblanc, P. Lecieux, S. Lecleire, N. Leclerc, C. Le Couteulx, J. Ledent, J. Lefebvre, P. Lefiliatre, C. Le Goffic, C. Legrand, A. Le Grix, P. Lelong, B. Leluyer, C. Lemaitre, C. Lenaerts, G. Lepeut, L. Lepileur, A. Leplat, E. Lepoutre‐Dujardin, H. Leroi, M.Y. Leroy, P. Le Roy, B. Lesage, Jp. Lesage, X. Lesage, J. Lesage, I. Lescanne‐Darchis, J. Lescut, D. Lescut, B. Leurent, P. Levy, M. Lhermie, L. Libier, A. Lion, B. Lisambert, I. Loge, F. Loire, J. Loreau, S. Louf, A. Louvet, L. Lubret, M. Luciani, D. Lucidarme, J. Lugand, O. Macaigne, D. Maetz, D. Maillard, H. Mancheron, O. Manolache, Ab. Marks‐Brunel, C. Marre, R. Marti, F. Martin, G. Martin, E. Marzloff, P. Mathurin, J. Mauillon, V. Maunoury, J.L. Maupas, Ma. Medam Djomo, C. Mechior, Z. Melki, B. Mesnard, P. Metayer, L. Methari, B. Meurisse, F. Meurisse, L. Michaud, X. Mirmaran, P. Modaine, A. Monthe, L. Morel, P.E. Mortier, E. Moulin, O. Mouterde, N. Mozziconaci, J. Mudry, M. Nachury, Md. Ngo, E. N'Guyen Khac, B. Notteghem, V. Ollevier, A. Ostyn, A. Ouraghi, B. Oussadou, D. Ouvry, B. Paillot, C. Painchart, N. Panien‐Claudot, C. Paoletti, A. Papazian, B. Parent, B. Pariente, Jc. Paris, P. Patrier, T. Paupard, B. Pauwels, M. Pauwels, E. Penninck, R. Petit, M. Piat, S. Piotte, C. Plane, B. Plouvier, E. Pollet, P. Pommelet, D. Pop, C. Pordes, G. Pouchain, P. Prades, A. Prevost, Jc. Prevost, G. Quartier, B. Quesnel, A.M. Queuniet, Jf. Quinton, A. Rabache, P. Rabelle, G. Raclot, S. Ratajczyk, D. Rault, V. Razemon, N. Reix, T. Renaut‐Vantroys, M. Revillion, G. Riachi, C. Richez, P. Robinson, J. Rodriguez, J. Roger, J.M. Roux, A. Rudelli, A. Saber, G. Savoye, P. Schlossberg, D. Sefrioui, M. Segrestin, D. Seguy, C. Seminur, M. Serin, A. Seryer, F. Sevenet, N. Shekh, J. Silvie, V. Simon, C. Spyckerelle, N. Talbodec, N. Tavernier, H. Tchandeu, A. Techy, J.L. Thelu, A. Thevenin, H. Thiebault, J. Thomas, J.M. Thorel, C. Thuillier, G. Tielman, M. Tode, J. Toisin, J. Tonnel, Jy. Touchais, P. Toumelin, Y. Touze, J.L. Tranvouez, C. Triplet, N. Triki, D. Turck, S. Uhlen, E. Vaillant, C. Valmage, D. Vanco, N. Vandaele‐Bertiaux, H. Vandamme, E. Vanderbecq, E. Vander Eecken, P. Vandermolen, P. Vandevenne, L. Vandeville, A. Vandewalle, C. Vandewalle, P. Vaneslander, J.P. Vanhoove, A. Vanrenterghem, C. Vanveuren, P. Varlet, I. Vasies, G. Verbiese, J. Verlynde, G. Vernier‐Massouille, P. Vermelle, C. Verne, P. Vezilier‐Cocq, B. Vigneron, M. Vincendet, J. Viot, Y.M. Voiment, A. Wacrenier, L. Waeghemaecker, J.Y. Wallez, M. Wantiez, F. Wartel, J. Weber, J.L. Willocquet, N. Wizla, E. Wolschies, O. Zaharia, S. Zaoui, A. Zalar, B. Zaouri, A. Zellweger, C. Ziade +480 morewiley +1 more sourceSevere eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab
, 2017 Corrado Pelaia,1 Alessandro Vatrella,2 Maria Teresa Busceti,1 Luca Gallelli,3 Rosa Terracciano,3 Rocco Savino,3 Girolamo Pelaia1 1Department of Medical and Surgical Sciences, Section of Respiratory Diseases, University “Magna Græcia&rdquo ...Vatrella A, Gallelli L, Savino R, Busceti MT, Pelaia C, Terracciano R, Pelaia G +6 morecore EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]
, 2013 Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...Donna E Davies, Cornelius Victoria, Grégory Seumois, Lau, LC, Karl J Staples, Cornelius, Victoria, Dorinsky, P, Victoria Cornelius, Davies Donna E., Dinesh Bagmane (457229), Staples, Karl J., Uddin, Mohib, Ratko Djukanović, Pandurangan Vijayanand, Victoria Cornelius (457230), Lau, Laurie C., Mohib Uddin (457226), Karl J. Staples (457228), Bagmane, Dinesh, Ratko Djukanović (457232), Paul Dorinsky, Pandurangan Vijayanand (277869), Djukanović Ratko, Lau, Laurie C, Grégory Seumois (5656213), Lau Laurie C., Staples, KJ, Vijayanand, P, Vijayanand, Pandurangan, Laurie C. Lau (457227), Seumois, G, Uddin, M, Staples, Karl J, Davies, Donna E, Staples Karl J., Davies, DE, Donna E. Davies (137702), Seumois Grégory, Djukanović, R, Dinesh Bagmane, Djukanović, Ratko, Cornelius, V, Davies, Donna E., Laurie C Lau, Dorinsky Paul, Paul Dorinsky (457231), Dorinsky, Paul, Seumois, Grégory, Bagmane Dinesh, Uddin Mohib, Bagmane, D, Mohib Uddin, Vijayanand Pandurangan +52 morecore +2 more sourcesDiagnosis and management of eosinophilic asthma: a US perspective
Journal of Asthma and Allergy, 2014 Hannah H Walford,1,2 Taylor A Doherty11Department of Medicine, 2Department of Pediatrics, University of California, La Jolla, CA, USAAbstract: Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of ...Walford HH, Doherty TAdoaj Eosinophil Peroxidase Activity is a Reliable and Resilient Biomarker for Eosinophilic Chronic Rhinosinusitis
International Forum of Allergy &Rhinology, EarlyView.Christian Caceres, Evan D. Marsh, Kristine A. Smith, Chelsea E. Pollard, Fok Vun Chan, Fatemeh Zarei Haji Abadi, Prince A. B. Minkah, Paul O. Neilsen, Justin R. Savage, Bryan R. McRae, Benjamin L. Witt, Jeremiah A. Alt, Gretchen M. Oakley, Richard R. Orlandi, Abigail Pulsipher +14 morewiley +1 more source