Results 31 to 40 of about 316,727 (384)
Pharmacology Research & Perspectives, 2020 Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate ...
Yanaika Shari Sabogal Piñeros +8 more
doaj +1 more source
Cells, 2021 New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...]
Stephane Esnault +2 more
doaj +1 more source
Eosinophils and eosinophil-associated diseases: An update. [PDF]
Journal of Allergy and Clinical Immunology, 2017 The goal of this series is to offer a survey of the latest literature for clinicians and scientists alike, providing a list of important recent advances relevant to the broad field of allergy and immunology. This particular assignment was to cover the topic of eosinophils. In an attempt to highlight major ideas, themes, trends, and advances relevant to
Jeremy A O'Sullivan, B. Bochner
semanticscholar +3 more sources
Production of monoclonal antibodies reactive with ovine eosinophils
BMC Immunology, 2007 Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT +3 more
doaj +1 more source
Eosinophils from Physiology to Disease: A Comprehensive Review
BioMed Research International, 2018 Despite being the second least represented granulocyte subpopulation in the circulating blood, eosinophils are receiving a growing interest from the scientific community, due to their complex pathophysiological role in a broad range of local and systemic
G. Ramirez +9 more
semanticscholar +1 more source
Dual function of eosinophils in pathogenesis and protective immunity against parasites
Memorias do Instituto Oswaldo Cruz, 1992 The functional duality of eosinophils, involved in a protective response or in pathogenesis is illustrated in various parasitic infections. In schistosomiasis, eosinophils have been shown to mediate schistosomula killing, in the presence of antibodies ...
Monique Capron
doaj +1 more source
Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions [PDF]
, 2018 Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen(s), and individuals may ...
Gupta, Sandeep K., Naramore, Sara
core +1 more source
Anti-IL5 Drugs in COVID-19 Patients: Role of Eosinophils in SARS-CoV-2-Induced Immunopathology
Frontiers in Pharmacology, 2021 SARS-CoV-2 infection stimulates a complex activation of the immune system. Eosinophils belong to the host’s defense equipment against respiratory viruses.
Daniele Pala +3 more
doaj +1 more source
Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 [PDF]
, 2016 Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic inflammatory disorders. However, its role in allergic airway inflammation has not yet been elucidated.
Abramoff +15 more
core +1 more source
Eosinophils: The unsung heroes in cancer?
Oncoimmunology, 2018 Prolonged low-grade inflammation or smoldering inflammation is a hallmark of a cancer. Eosinophils are components of the immune microenvironment that modulates tumor initiation and progression.
G. Varricchi +7 more
semanticscholar +1 more source