Results 21 to 30 of about 23,392 (228)

Tumour-Associated Tissue Eosinophilia in Oral Squamous Cell Carcinoma- A Boon or a Bane? [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The infiltration of tumour stroma by eosinophils, Tumour-Associated Tissue Eosinophilia (TATE) is known to modulate the evolution of Oral Squamous Cell Carcinoma (OSCC).
Shweta Yellapurkar   +7 more
doaj   +1 more source

Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells

open access: yesCellular Immunology, 2003
Eotaxin-1/CCL11, eotaxin-2/CCL24, and eotaxin-3/CCL26 bind specifically and exclusively to CC chemokine receptor (CCR) 3, which is a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Bronchial epithelial cells represent an important source of chemokines, and thus we investigated in vitro ...
Akiko, Komiya   +12 more
openaire   +4 more sources

The “Aging Factor” Eotaxin-1 (CCL11) Is Detectable in Transfusion Blood Products and Increases with the Donor’s Age

open access: yesFrontiers in Aging Neuroscience, 2017
Background: High blood levels of the chemokine eotaxin-1 (CCL11) have recently been associated with aging and dementia, as well as impaired memory and learning in humans. Importantly, eotaxin-1 was shown to pass the blood-brain-barrier (BBB) and has been
Julia Hoefer   +5 more
doaj   +1 more source

Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine Eotaxin-1 in colorectal cancer patients

open access: yesWorld Journal of Surgical Oncology, 2007
Background Previous studies suggest that chemokines (chemotactic cytokines) promote and regulate neoplastic progression including metastasis and angiogenesis. The chemokine eotaxin-1 is a powerful eosinophil attractant but also exerts chemotaxis of other
Dienus Olaf   +4 more
doaj   +1 more source

EVALUATION AND CLINICAL SIGNIFICANCE OF CHEMOKINES AND THEIR SPECIFIC RECEPTORS IN PATIENTS WITH BRONCHIAL ASTHMA

open access: yesМедицинская иммунология, 2014
. A group of patients with bronchial asthma (BA) was under investigation, being classified according to their disease activity, and exacerbation risk factors.
A. A. Bibkova   +6 more
doaj   +1 more source

Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes

open access: yesJournal of Biomedical Science, 2011
Background Osteoarthritis (OA) is characterized by the degradation of articular cartilage, marked by the breakdown of matrix proteins. Studies demonstrated the involvement of chemokines in this process, and some may potentially serve as diagnostic ...
Chao Pin-Zhir   +4 more
doaj   +1 more source

The Effect of IL-35 on the Expression of Nasal Epithelial-Derived Proinflammatory Cytokines

open access: yesMediators of Inflammation, 2021
Background. Airway epithelium plays an important role during the development of allergic rhinitis (AR), which is characterized by production of thymic stromal lymphopoietin (TSLP), interleukin 33 (IL-33), and interleukin 25 (IL-25).
Mingrong Nie   +5 more
doaj   +1 more source

Effects of NB-UVB with pimecrolimus cream on the expression of eotaxin in serum and CCR3 on peripheral blood monocytes in patients with adult atopic dermatitis

open access: yesPifu-xingbing zhenliaoxue zazhi, 2020
Objective: To compare expression levels of eotaxin in the serum and CCR3 on the peripheral blood monocytes (PBMC) prior to and after the treatment with NB-UVB plus pimecrolimus cream, in order to elucidate the pathogenesis of atopic dermatitis(AD ...
Yan YANG   +9 more
doaj   +1 more source

Bullous pemphigoid—What do we know about the most recent therapies?

open access: yesFrontiers in Medicine, 2022
IntroductionBullous pemphigoid (BP) is the most common subtype of autoimmune blistering diseases that primarily affects the elderly and is classically defined by the presence of IgG and/or complement C3 against the BP180 and BP230 hemidesmosome proteins.
Faith A. P. Zeng   +3 more
doaj   +1 more source

5-Lipoxygenase-Dependent Recruitment of Neutrophils and Macrophages by Eotaxin-Stimulated Murine Eosinophils

open access: yesMediators of Inflammation, 2014
The roles of eosinophils in antimicrobial defense remain incompletely understood. In ovalbumin-sensitized mice, eosinophils are selectively recruited to the peritoneal cavity by antigen, eotaxin, or leukotriene(LT)B4, a 5-lipoxygenase (5-LO) metabolite ...
Ricardo Alves Luz   +8 more
doaj   +1 more source

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