Results 51 to 60 of about 23,392 (228)

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee   +4 more
wiley   +1 more source

Cross-Species Analysis of Glycosaminoglycan Binding Proteins Reveals Some Animal Models Are “More Equal” than Others

open access: yesMolecules, 2019
Glycosaminoglycan (GAG) mimetics are synthetic or semi-synthetic analogues of heparin or heparan sulfate, which are designed to interact with GAG binding sites on proteins.
Eric D. Boittier   +3 more
doaj   +1 more source

Eotaxin-3 immunostaining of esophageal biopsy specimens.

open access: yes, 2014
(A) Normal squamous epithelium shows no eotaxin-3 immunostaining. (B) Eotaxin-3 labels epithelial cells with variable intensity in biopsies with esophageal eosinophilia. (C) High power magnification (1000x) identifies a granular cytoplasmic staining that
Xi Zhang (83736)   +5 more
core   +1 more source

Eotaxin: an important chemokine in asthma [PDF]

open access: yes, 2006
peer reviewedWe know that the eosinophil plays an important role in asthma pathogenesis. This polynuclear cell is attracted into the airways by several chemokines. Eotaxin is one of them. Endothelial cells, smooth muscle cells, epithelial cells, alveolar
Hemelaers, L., Louis, Renaud
core   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Ursodeoxycholic Acid Reduces Angiotensin-Converting Enzyme 2 Activity and Suppresses Cytokine Storm Syndrome in Patients With Coronavirus Disease 2019. [PDF]

open access: yesMedComm (2020)
SARS‐CoV‐2 infection causes COVID‐19 and stimulates immune cells, such as dendritic cells, monocytes, and macrophages, to increase levels of many cytokines. Ursodeoxycholic acid (UDCA) inhibits farnesoid X receptor (FXR), resulting in a decrease in the activity of angiotensin‐converting enzyme 2 (ACE2), the main receptor on the membrane for SARS‐CoV‐2.
Tong Z   +8 more
europepmc   +2 more sources

Serum C-C motif ligand 11/Eotaxin-1 may serve as a candidate biomarker for postmenopausal osteoporosis [PDF]

open access: yesJournal of Medical Biochemistry, 2019
Background: The chemokine C-C motif ligand 11, also known as eotaxin-1, has been identified as a novel mediator of inflammatory bone resorption. However, little is known regarding a potential role for CCL11/Eotaxin-1 in postmenopausal osteoporosis ...
Wang Wen   +6 more
doaj  

Eosinophil-active chemokines: assessment of in vivo activity

open access: yesBrazilian Journal of Medical and Biological Research, 1998
The selective recruitment of eosinophils in tissue is a striking feature of allergic diseases. Recently, a family of chemoattractant molecules, namely chemokines, has been described which potently activates eosinophil function in vitro. We have developed
M.M. Teixeira
doaj   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen   +3 more
wiley   +1 more source

MHC Class II Activation and Interferon-γ Mediate the Inhibition of Neutrophils and Eosinophils by Staphylococcal Enterotoxin Type A (SEA)

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Staphylococcal enterotoxins are classified as superantigens that act by linking T-cell receptor with MHC class II molecules, which are expressed on classical antigen-presenting cells (APC).
Ana P. Ferreira-Duarte   +5 more
doaj   +1 more source

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