Reversal of Postnatal Brain Astrocytes and Ependymal Cells towards a Progenitor Phenotype in Culture [PDF]
CellsAstrocytes and ependymal cells have been reported to be able to switch from a mature cell identity towards that of a neural stem/progenitor cell. Astrocytes are widely scattered in the brain where they exert multiple functions and are routinely targeted ...
Dimitrios Kakogiannis +3 more
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Foxj1a is expressed in ependymal precursors, controls central canal position and is activated in new ependymal cells during regeneration in zebrafish [PDF]
Open Biology, 2017 Zebrafish are able to regenerate the spinal cord and recover motor and sensory functions upon severe injury, through the activation of cells located at the ependymal canal.
Ana Ribeiro +4 more
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Musashi and Plasticity of Xenopus and Axolotl Spinal Cord Ependymal Cells [PDF]
Frontiers in Cellular Neuroscience, 2018 The differentiated state of spinal cord ependymal cells in regeneration-competent amphibians varies between a constitutively active state in what is essentially a developing organism, the tadpole of the frog Xenopus laevis, and a quiescent, activatable ...
Ellen A. G. Chernoff +4 more
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TMEM106B amyloid filaments in the Biondi bodies of ependymal cells. [PDF]
Acta NeuropatholBiondi bodies are filamentous amyloid inclusions of unknown composition in ependymal cells of the choroid plexuses, ependymal cells lining cerebral ventricles and ependymal cells of the central canal of the spinal cord. Their formation is age-dependent and they are commonly associated with a variety of neurodegenerative conditions, including Alzheimer ...
Ghetti B +14 more
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Addressing the Effect of Exercise on Glial Cells: Focus on Ependymal Cells
Journal of Integrative NeuroscienceA growing body of research highlights the positive impact of regular physical activity on improving physical and mental health. On the other hand, physical inactivity is one of the leading risk factors for noncommunicable diseases and death worldwide ...
Grazia Maugeri +4 more
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Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members. [PDF]
Neuron, 2019 Adult neural stem cells and multiciliated ependymal cells are glial cells essential for neurological functions. Together, they make up the adult neurogenic niche.
Ortiz-Álvarez G +13 more
europepmc +5 more sources
The Structure of the Spinal Cord Ependymal Region in Adult Humans Is a Distinctive Trait among Mammals [PDF]
Cells, 2021 In species that regenerate the injured spinal cord, the ependymal region is a source of new cells and a prominent coordinator of regeneration. In mammals, cells at the ependymal region proliferate in normal conditions and react after injury, but in ...
Alejandro Torrillas de la Cal +7 more
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Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice. [PDF]
Sci Rep, 2022 Abstract The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-kB signalling, RELA (ZFTA-RELA), is expressed in more than two-thirds of supratentorial ependymoma (ST-EPN-RELA), but ZFTA’s expression profile and functional analysis in multiciliated ependymal (E1 ...
Herranz-Pérez V +5 more
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Six3 is required for ependymal cell maturation
Development, 2011 Ependymal cells are part of the neurogenic niche in the adult subventricular zone of the lateral ventricles, where they regulate neurogenesis and neuroblast migration. Ependymal cells are generated from radial glia cells during embryonic brain development and acquire their final characteristics postnatally.
Alfonso, Lavado, Guillermo, Oliver
openaire +4 more sources
The mouse Jhy gene regulates ependymal cell differentiation and ciliogenesis. [PDF]
PLoS ONE, 2017 During the first postnatal week of mouse development, radial glial cells lining the ventricles of the brain differentiate into ependymal cells, undergoing a morphological change from pseudostratified cuboidal cells to a flattened monolayer.
Hilmarie Muniz-Talavera +1 more
doaj +2 more sources