Results 21 to 30 of about 25,194 (189)

Ependymal Cells Require Anks1a for Their Proper Development. [PDF]

Mol Cells, 2019
Ependymal cells constitute the multi-ciliated epithelium, which lines the brain ventricular lumen. Although ependymal cells originate from radial glial cells in the perinatal rodent brain, the exact mechanisms underlying the full differentiation of ependymal cells are poorly understood.
Park S, Lee H, Lee J, Park E, Park S.
europepmc   +3 more sources

Transcriptional regulation of ependymal cell maturation within the postnatal brain

Neural Development, 2018
Background Radial glial stem cells within the developing nervous system generate a variety of post-mitotic cells, including neurons and glial cells, as well as the specialised multi-ciliated cells that line the walls of the ventricular system, the ...
Diana Vidovic, Raul Ayala Davila, Richard M. Gronostajski, Tracey J. Harvey, Michael Piper   +4 more
doaj   +2 more sources

Ependymal cell inflammatory activation in response to intracerebral hemorrhage [PDF]

Journal of Neuroinflammation
Background Neuroinflammation is a central pathological process in secondary brain injury following intracerebral hemorrhage (ICH). While inflammatory responses in perihematomal brain tissue have been extensively investigated, the contribution of ...
Jing Liu, Haopu Lin, Xuefeng He, Yonghe Zheng, Jianan Wu, Qizhen He, Cheng Zhang, Huaping Huang, Xian Yu, Yinan Zhou, Zihang Chen, Hang Zhou, Linfeng Fan, Xiongjie Fu, Tianchi Tang, Guannan Guan, Xiaobo Yu, Xiuqin Feng, Yushen Du, Huaijun Chen, Jingyin Chen   +20 more
doaj   +2 more sources

Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus

Cell Reports, 2017
Motile cilia in ependymal cells, which line the cerebral ventricles, exhibit a coordinated beating motion that drives directional cerebrospinal fluid (CSF) flow and guides neuroblast migration.
Maki Takagishi, Masato Sawada, Shinya Ohata, Naoya Asai, Atsushi Enomoto, Kunihiko Takahashi, Liang Weng, Kaori Ushida, Hosne Ara, Shigeyuki Matsui, Kozo Kaibuchi, Kazunobu Sawamoto, Masahide Takahashi   +12 more
doaj   +2 more sources

Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor

Cell Reports, 2019
Summary: The adult mouse brain contains an extensive neurogenic niche in the lateral walls of the lateral ventricles. This epithelium, which has a unique pinwheel organization, contains multiciliated ependymal (E1) cells and neural stem cells (B1).
Stephanie A. Redmond, María Figueres-Oñate, Kirsten Obernier, Marcos Assis Nascimento, Jose I. Parraguez, Laura López-Mascaraque, Luis C. Fuentealba, Arturo Alvarez-Buylla   +7 more
doaj   +3 more sources

Impact of aquaporin-4 and CD11c + microglia in the development of ependymal cells in the aqueduct: inferences to hydrocephalus. [PDF]

Fluids Barriers CNS
AQP4 is expressed in the endfeet membranes of subpial and perivascular astrocytes and in the ependymal cells that line the ventricular system. The sporadic appearance of obstructive congenital hydrocephalus (OCHC) has been observed in the offspring of ...
Mayo F, González-Vinceiro L, Hiraldo-González L, Rodríguez-Gómez FD, Calle-Castillejo C, Mayo M, Netti V, Ramírez-Lorca R, Echevarría M.   +8 more
europepmc   +2 more sources

Mechanisms of ependymal cells specification

, 2018
Ependymal cells are multiciliated cells lining the walls of all brain cavities. Once they are mature, they do not divide during life. Their motile ciliary beating endorses a crucial role in maintaining a proper flow of cerebrospinal fluid throughout all brain cavities. Ependymal cells also ensure critical molecular exchanges of the cerebrospinal fluid.
Daclin, Marie
openaire   +2 more sources

Ependymal cells and astrocytes generate neurons.

Folia morphologica, 2000
Recent studies have showed that the ependymal cells and subventricular zone astrocytes are neurosphere-initiating cells and are neural stem cells. They give rise to neurons and glial cells in response to injury and utilization of endogenous stem cells in the treatment of nervous system diseases is important strategy in neurogenesis.
W, Woźniak
openaire   +2 more sources

Ependymal cells and multiple sclerosis: proposing a relationship.

Neural Regen Res, 2020
Hatrock D, Caporicci-Dinucci N, Stratton JA.   +2 more
europepmc   +4 more sources

Interleukin-17A regulates ependymal cell proliferation and functional recovery after spinal cord injury in mice

Cell Death and Disease, 2021
Ependymal cells have been suggested to act as neural stem cells and exert beneficial effects after spinal cord injury (SCI). However, the molecular mechanism underlying ependymal cell regulation after SCI remains unknown.
Hisao Miyajima, Takahide Itokazu, Shogo Tanabe, Toshihide Yamashita   +3 more
doaj   +1 more source