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Trapping of Carbonyl Compounds by Epicatechin: Reaction Kinetics and Identification of Epicatechin Adducts in Stored UHT Milk

Journal of Agricultural and Food Chemistry, 2020
The kinetics of the reaction between epicatechin and various carbonyl compounds typically formed in cooked and stored foods were evaluated in model systems at pH 7.4 and 37 °C, and the corresponding reaction products in stored ultrahigh temperature (UHT) milk-added epicatechin were identified by high-performance liquid chromatography-tandem mass ...
Hongkai Zhu   +3 more
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Characterization of Sulfated Quercetin and Epicatechin Metabolites

Journal of Agricultural and Food Chemistry, 2012
Different monosulfates of quercetin and epicatechin with metabolic interest were obtained by hemisynthesis and characterized regarding their chromatographic behavior and absorption and mass spectra. Three of these compounds were further isolated, and their structures were elucidated by mass spectrometry and (1)H and (13)C nuclear magnetic resonance ...
Montserrat, Dueñas   +4 more
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Die absolute Konfiguration des (−)‐Epicatechins

Helvetica Chimica Acta, 1960
AbstractErschöpfende Ozonisierung von (−)‐Epicatechin und Reduktion der optisch aktiven Ozonisierungsprodukte führte zu 2‐Desoxy‐D‐xylit, welcher als Tetraphenylurethan in reiner Form isoliert, charakterisiert und identifiziert wurde. Der von D‐Glycerinaldehyd sterisch eindeutig abgeleitete 2‐Desoxy‐D‐xylit enthält die beiden asymmetrischen C‐Atome 2 ...
A. Züst, F. Lohse, E. Hardegger
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Effects of epicatechin on rat islets of Langerhans

Diabetes, 1984
Plants containing epicatechin (a flavonoid) have been used to treat diabetes mellitus in Indian medicine. The present study reports effects of this compound on isolated islets of Langerhans. The flavonoid (1 mM) was found to increase insulin secretion from isolated rat islets of Langerhans in the presence of either 2 or 20 mM glucose, in static ...
C S, Hii, S L, Howell
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Synthesis of B-ring-fluorinated (−)-epicatechin gallate derivatives

Organic & Biomolecular Chemistry, 2020
Electronically modified, fluorinated catechins and epicatechins are enantioselectively synthesized in a short, convergent sequence via kinetic resolution.
David D. S. Thieltges   +3 more
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Biological activities of (−)-epicatechin and (−)-epicatechin-containing foods: Focus on cardiovascular and neuropsychological health

Biotechnology Advances, 2018
Recent studies have suggested that certain (-)-epicatechin-containing foods have a blood pressure-lowering capacity. The mechanisms underlying (-)-epicatechin action may help prevent oxidative damage and endothelial dysfunction, which have both been associated with hypertension and certain brain disorders.
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On the Mechanism of Metabolism of (−)-Epicatechin

Bulletin of the Agricultural Chemical Society of Japan, 1960
(−)-Epicatechin was administered orally to rabbits and vanillic acid, 3-hydroxybenzoic acid, protocatechuic acid, and three kinds of neutral substances were found to be excreted in the urine. The three kinds of neutral substances were identified as 1-δ-(3-methoxy-4-hydroxyphenyl)-, 1-δ-(3-hydroxyphenyl)-, and 1-δ-(3,4-dihydroxyphenyl)-γ-valerolactones,
Yasuyoshi OHSHIMA   +2 more
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(+)-Catechin and (−)-epicatechin in Bulgarian fruits

Journal of Food Composition and Analysis, 2005
Abstract Fifteen different fruits were analyzed. (+)-Catechin and (−)-epicatechin were determined with RP-HPLC and fluorescence detection. The LOD and LOQ are 0.1 and 0.3 mg/kg fresh weight, respectively. The uncertainty of determination is Δ ¯ u = ± 0.3 mg / kg for (+)-catechin and Δ ¯ u = ± 0.8 mg /
Silvia Tsanova-Savova   +2 more
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Inhibitory effect of epicatechin gallate on protein glycation

Food Research International, 2019
Protein glycation can produce the advanced glycation end products (AGEs), which has a potential health risk due to its relevance with diabetic complications. Searching for potent inhibitors to suppress hyperglycemia-induced protein glycation is of great significance.
Xiaqing Wu   +5 more
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Effects of (−)-epicatechin on hepatic triglyceride metabolism

Food & Function
(−)-Epicatechin (EC) consumption promotes changes in liver lipid homeostasis by increasing hepatic TG levels and DGAT2 and PPARα expression in mice. In human HepG2 cells, EC and its metabolites did not replicate these effects on TG accumulation.
Zahra Mostofinejad   +3 more
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