Results 21 to 30 of about 377,291 (237)
Conjunctival reconstruction with progenitor cell-derived autologous epidermal sheets in rhesus monkey. [PDF]
PLoS ONE, 2011 Severe ocular surface diseases are some of the most challenging problems that the clinician faces today. Conventional management is generally unsatisfactory, and the long-term ocular consequences of these conditions are devastating.
Rong Lu +6 more
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AQP5 regulates the proliferation and differentiation of epidermal stem cells in skin aging [PDF]
Brazilian Journal of Medical and Biological Research, 2020 The epidermis, the outermost layer of the skin, is the first barrier that comes into contact with the external environment. It plays an important role in resisting the invasion of harmful substances and microbial infections. The skin changes with age and
Jing Zhou +5 more
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Multi‐tasking epidermal stem cells: Beyond epidermal maintenance [PDF]
Development, Growth & Differentiation, 2018 Over the past decade, multiple stem cell compartments have been identified within the epidermis. These stem cell pools have different transcriptional properties, proliferative modes and anatomical locations, and they maintain distinct epidermal compartments.
Hironobu Fujiwara +2 more
openaire +2 more sources
Targeting epidermal Langerhans cells by epidermal powder immunization [PDF]
Cell Research, 2002 Immune reactions to foreign or self-antigens lead to protective immunity and, sometimes, immune disorders such as allergies and autoimmune diseases. Antigen presenting cells (APC) including epidermal Langerhans cells (LCs) play an important role in the course and outcome of the immune reactions.
Dexiang, Chen, Lendon G, Payne
openaire +2 more sources
Stem Cell Research & Therapy, 2022 Background Efficient re-epithelialization is important for successful skin wound healing. The proportion of epidermal stem cells (EpSCs) and dendritic epidermal T cells (DETCs) determines the extent of wound re-epithelialization, especially in large ...
Mian Liu +14 more
doaj +1 more source
Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila. [PDF]
PLoS ONE, 2013 After injury to the animal epidermis, a variety of genes are transcriptionally activated in nearby cells to regenerate the missing cells and facilitate barrier repair. The range and types of diffusible wound signals that are produced by damaged epidermis
Rachel A Patterson +5 more
doaj +1 more source
Epigenetics, 2020 Post-translational modifications on nucleosomal histones represent a key epigenetic regulatory mechanism to mediate the complex gene expression, DNA replication, and cell cycle changes that occur in embryonic cells undergoing lineage specification ...
Yan Ting Shue +6 more
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Role of bulge epidermal stem cells and TSLP signaling in psoriasis
EMBO Molecular Medicine, 2019 Psoriasis is a common inflammatory skin disease involving a cross‐talk between epidermal and immune cells. The role of specific epidermal stem cell populations, including hair follicle stem cells (HF‐SCs) in psoriasis is not well defined.
Nuria Gago‐Lopez +6 more
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Hair follicle epidermal stem cells define a niche for tactile sensation
eLife, 2018 The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive.
Chun-Chun Cheng +13 more
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Stem Cells International, 2016 Inconsistent with the view that epidermal stem cells reside randomly spread along the basal layer of the epidermal rete ridges, we found that epidermal cells expressing stem cell markers in nonglabrous skin exist in direct connection with the distal end ...
N. Torkamani +3 more
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