Results 31 to 40 of about 5,214,788 (302)

AQP5 regulates the proliferation and differentiation of epidermal stem cells in skin aging [PDF]

Brazilian Journal of Medical and Biological Research, 2020
The epidermis, the outermost layer of the skin, is the first barrier that comes into contact with the external environment. It plays an important role in resisting the invasion of harmful substances and microbial infections. The skin changes with age and
Jing Zhou, Yabing Dong, Jianlan Liu, Jie Ren, Jinyan Wu, Ningwen Zhu   +5 more
doaj   +2 more sources

Granulocyte-activating mediators (GRAM) [PDF]

, 1987
In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A., Zeck-Kapp, G., Möller, A., Putz, Reinhard, A. Kapp, E. Sch�pf, T. A. Luger, C. Hauser, M. Danner   +8 more
core   +1 more source

Analysis of the mechanisms of resistance to Epidermal growth factor receptor inhibitors and development of multiple targeted strategies [PDF]

, 2008
Background. Primary and acquired resistance to selective Epidermal growth factor receptor (EGFR) inhibitors remains the most significant obstacle to the success of these targeted agents in cancer therapy.
Rosa, Roberta
core   +1 more source

Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]

, 2003
Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi, Takahashi, Sumio, Takeuchi, Sakae, Oomizu, Souichi, Sharma, Seema, Masui, Tohru   +5 more
core   +1 more source

Targeting epidermal Langerhans cells by epidermal powder immunization [PDF]

Cell Research, 2002
Immune reactions to foreign or self-antigens lead to protective immunity and, sometimes, immune disorders such as allergies and autoimmune diseases. Antigen presenting cells (APC) including epidermal Langerhans cells (LCs) play an important role in the course and outcome of the immune reactions.
Dexiang, Chen, Lendon G, Payne
openaire   +2 more sources

Dendritic epidermal T cells secreting exosomes promote the proliferation of epidermal stem cells to enhance wound re-epithelialization

Stem Cell Research & Therapy, 2022
Background Efficient re-epithelialization is important for successful skin wound healing. The proportion of epidermal stem cells (EpSCs) and dendritic epidermal T cells (DETCs) determines the extent of wound re-epithelialization, especially in large ...
Mian Liu, Zhihui Liu, Yunxia Chen, Shiya Peng, Jiacai Yang, Cheng Chen, Jue Wang, Ruoyu Shang, Yuanyang Tang, Yong Huang, Xiaorong Zhang, Xiaohong Hu, Yih-Cherng Liou, Gaoxing Luo, Weifeng He   +14 more
doaj   +1 more source

Update on HER-2 as a target for cancer therapy: alternative strategies for targeting the epidermal growth factor system in cancer [PDF]

, 2001
The epidermal growth factor (EGF) family of ligands and receptors interact to influence cell division, differentiation and motility. Much evidence supports their importance in causing and sustaining cell transformation in model systems and in human ...
Gullick, William J.
core   +1 more source

Serine proteolytic pathway activation reveals an expanded ensemble of wound response genes in Drosophila. [PDF]

PLoS ONE, 2013
After injury to the animal epidermis, a variety of genes are transcriptionally activated in nearby cells to regenerate the missing cells and facilitate barrier repair. The range and types of diffusible wound signals that are produced by damaged epidermis
Rachel A Patterson, Michelle T Juarez, Anita Hermann, Roman Sasik, Gary Hardiman, William McGinnis   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source