Results 41 to 50 of about 5,214,788 (302)
Hair follicle germinative epidermal cells: a molecular study [PDF]
, 1999 At the base of the hair follicle epidermal matrix is a population of germinative epidermal (GE) cells that is in close communication with the dermal papilla.
Whitehouse, C.J. +1 more
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Epidermal Stem Cells of the Skin [PDF]
Annual Review of Cell and Developmental Biology, 2006 The skin constantly renews itself throughout adult life, and the hair follicle undergoes a perpetual cycle of growth and degeneration. Stem cells (SCs) residing in the epidermis and hair follicle ensure the maintenance of adult skin homeostasis and hair regeneration, but they also participate in the repair of the epidermis after injuries. We summarize
Blanpain, Cédric, Fuchs, Elaine
openaire +3 more sources
Role of bulge epidermal stem cells and TSLP signaling in psoriasis
EMBO Molecular Medicine, 2019 Psoriasis is a common inflammatory skin disease involving a cross‐talk between epidermal and immune cells. The role of specific epidermal stem cell populations, including hair follicle stem cells (HF‐SCs) in psoriasis is not well defined.
Nuria Gago‐Lopez +6 more
doaj +1 more source
Hair follicle epidermal stem cells define a niche for tactile sensation
eLife, 2018 The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive.
Chun-Chun Cheng +13 more
doaj +1 more source
Epigenetics, 2020 Post-translational modifications on nucleosomal histones represent a key epigenetic regulatory mechanism to mediate the complex gene expression, DNA replication, and cell cycle changes that occur in embryonic cells undergoing lineage specification ...
Yan Ting Shue +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Dermal and epidermal cell functions in the growth and regeneration of hair follicles and other skin appendages [PDF]
, 1998 Epithelial-mesenchymal interactions are central to the development of skin and skin appendages in vertebrates. These interactions continue throughout adult life and underpin the cyclic growth and loss of hair in mammals. While the molecular basis of such
Gharzi, Ahmad
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Breast tumor kinase (Brk/PTK6) plays a role in the differentiation of primary keratinocytes [PDF]
, 2011 This work was supported by a project grant from the Biotechnology and Biological Sciences Research Council, UKBreast Tumor Kinase (Brk/PTK6) has a relatively limited expression profile in normal tissue.
Tupper, J +5 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Histology of Alarm Substance Cells in Relation to Parasite Load and Fish Size for Hornyhead Chub (Nocomis biguttatus) [PDF]
, 2012 Color poster with text, images, diagrams, tables, and graphs.It is generally thought that alarm substance cells (ASC) found in fish epidermis evolved as a means of reducing predation risk via the release of a chemical substance these cells hold.
Meller, Megan +2 more
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