Results 21 to 30 of about 5,980,424 (294)
Inconsistent with the view that epidermal stem cells reside randomly spread along the basal layer of the epidermal rete ridges, we found that epidermal cells expressing stem cell markers in nonglabrous skin exist in direct connection with the distal end ...
N. Torkamani +3 more
doaj +1 more source
Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J +24 more
core +1 more source
Stem cells are by definition present in all self-renewing tissues and are believed to play a central role in cell growth and differentiation. Existing evidence suggests that a subpopulation of epidermal basal keratinocytes represents stem cells; however, these cells have never been positively identified.
Lavker, Robert M., Sun, Tung-Tien
openaire +2 more sources
Lineage Analysis of Epidermal Stem Cells [PDF]
Lineage tracing involves labeling cells to track their subsequent behavior within the normal tissue environment. The advent of genetic lineage tracing and cell proliferation assays, together with high resolution three-dimensional (3D) imaging and quantitative methods to infer cell behavior from lineage-tracing data, has transformed our understanding of
Maria P, Alcolea, Philip H, Jones
openaire +2 more sources
Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis
The presence of distinct stem cells that maintain the interfollicular epidermis is highly debated. Here, we report a population of keratinocytes, marked by Thy1, in the basal layer of the interfollicular epidermis. We find that epidermal cells expressing
Elle Koren +17 more
doaj +1 more source
EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
Summary: Epidermal growth factor receptor (EGFR) signaling controls skin development and homeostasis in mice and humans, and its deficiency causes severe skin inflammation, which might affect epidermal stem cell behavior.
Nicole Amberg +8 more
doaj +1 more source
Hair follicle epidermal stem cells define a niche for tactile sensation
The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive.
Chun-Chun Cheng +13 more
doaj +1 more source
Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate. [PDF]
Chermnykh E +2 more
europepmc +2 more sources
Neural crest-derived stem cells [PDF]
The neural crest is a transient embryonic structure in vertebrates that gives rise to most of the peripheral nervous system (PNS) and to several non-neural cell types, including smooth muscle cells of the cardiovascular system, pigment cells in the skin,
Sommer, L, Shakhova, O
core +1 more source
Summary: Epidermal homeostasis requires balanced and coordinated adult stem cell renewal and differentiation. These processes are controlled by both extracellular signaling and by cell intrinsic transcription regulatory networks, yet how these control ...
Roderick A.P.M. van Eijl +4 more
doaj +1 more source

