Results 11 to 20 of about 5,487,472 (290)

Epidermal Stem Cells and Their Epigenetic Regulation [PDF]

International Journal of Molecular Sciences, 2013
Stem cells play an essential role in embryonic development, cell differentiation and tissue regeneration. Tissue homeostasis in adults is maintained by adult stem cells resident in the niches of different tissues. As one kind of adult stem cell, epidermal stem cells have the potential to generate diversified types of progeny cells in the skin. Although
Shen, Qi, Jin, Hongchuan, Wang, Xian
openaire   +3 more sources

Role of bulge epidermal stem cells and TSLP signaling in psoriasis [PDF]

EMBO Molecular Medicine, 2019
Psoriasis is a common inflammatory skin disease involving a cross‐talk between epidermal and immune cells. The role of specific epidermal stem cell populations, including hair follicle stem cells (HF‐SCs) in psoriasis is not well defined.
Nuria Gago‐Lopez, Liliana F Mellor, Diego Megías, Guillermo Martín‐Serrano, Ander Izeta, Francisco Jimenez, Erwin F Wagner   +6 more
doaj   +2 more sources

Epidermal Stem Cells in Regenerative Medicine

, 2020
Stem cells present in the epidermis, and hair follicle, guarantee the conservation of adult skin maintenance and hair renewal, but they also play a pivotal role in wound repair and tissue regeneration. Adult stem cells present in the epidermis are also responsible for epidermis different layers' regeneration.We here summarize the epidermal stem cells ...
Martinotti, Simona, Marconato, Katia, Bonsignore, Gregorio, Ranzato, Elia   +3 more
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Revealing the Therapeutic Potential of Stem Cells in Burn Healing: A Deeper Understanding of the Therapeutic Mechanisms of Epidermal Stem Cells and Mesenchymal Stem Cells [PDF]

Stem Cells International
Conclusion: The present study obtained deep insight into the developing trends and research hotspots on burns associated with stem cells, which arouses growing concerns and implies increasing clinical implications.
Jianyu Lu, Wei Zhang, Yushu Zhu, Pengfei Luo, Xirui Tong, Sujie Xie, Luofeng Jiang, Xinya Guo, Jie Huang, Minyi Gu, Xinran Ding, Shuyuan Xian, Runzhi Huang, Shizhao Ji, Zhaofan Xia   +14 more
doaj   +2 more sources

Epidermal Stem Cells of the Skin [PDF]

Annual Review of Cell and Developmental Biology, 2006
The skin constantly renews itself throughout adult life, and the hair follicle undergoes a perpetual cycle of growth and degeneration. Stem cells (SCs) residing in the epidermis and hair follicle ensure the maintenance of adult skin homeostasis and hair regeneration, but they also participate in the repair of the epidermis after injuries. We summarize
Blanpain, Cédric, Fuchs, Elaine
openaire   +3 more sources

Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth

Stem Cell Research & Therapy, 2020
Millions suffer from skin diseases. Functional interfollicular epidermal stem cells are needed in skin therapy or drug screening in vitro. We obtained functional interfollicular epidermal stem cells with intact stemness and cell junctions by treating ...
Ling Leng, Jie Ma, Luye Lv, Wenjuan Wang, Dunqin Gao, Yunping Zhu, Zhihong Wu   +6 more
doaj   +1 more source

Gremlin 2 suppresses differentiation of stem/progenitor cells in the human skin

Regenerative Therapy, 2021
Introduction: The skin is comprised of various kinds of cells and has three layers, the epidermis, dermis and subcutaneous adipose tissue. Stem cells in each tissue duplicate themselves and differentiate to supply new cells that function in the tissue ...
Mika Kawagishi-Hotta, Seiji Hasegawa, Yu Inoue, Yuichi Hasebe, Masaru Arima, Yohei Iwata, Kazumitsu Sugiura, Hirohiko Akamatsu   +7 more
doaj   +1 more source

Biochemistry of epidermal stem cells [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2013
The epidermis is an important protective barrier that is essential for maintenance of life. Maintaining this barrier requires continuous cell proliferation and differentiation. Moreover, these processes must be balanced to produce a normal epidermis. The stem cells of the epidermis reside in specific locations in the basal epidermis, hair follicle and ...
Richard L, Eckert, Gautam, Adhikary, Sivaprakasam, Balasubramanian, Ellen A, Rorke, Mohan C, Vemuri, Shayne E, Boucher, Jackie R, Bickenbach, Candace, Kerr   +7 more
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Hair follicle epidermal stem cells define a niche for tactile sensation

eLife, 2018
The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive.
Chun-Chun Cheng, Ko Tsutsui, Toru Taguchi, Noriko Sanzen, Asako Nakagawa, Kisa Kakiguchi, Shigenobu Yonemura, Chiharu Tanegashima, Sean D Keeley, Hiroshi Kiyonari, Yasuhide Furuta, Yasuko Tomono, Fiona M Watt, Hironobu Fujiwara   +13 more
doaj   +1 more source

Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells [PDF]

, 2012
Widera D, Hauser S, Kaltschmidt C, Kaltschmidt B. Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy Research International.
Hauser, Stefan, Kaltschmidt, Christian, Widera, Darius, Widera, Darius ; https://orcid.org/, Kaltschmidt, Barbara   +4 more
core   +1 more source