Results 11 to 20 of about 5,134,709 (287)

Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization [PDF]

open access: yesStem Cell Research & Therapy, 2020
The skin, which serves as the first barrier of the human body, is particularly susceptible to exogenous injuries. Skin wounds, including acute burns and chronic non-healing ulcers, are commonly observed in clinics.
Tong Xiao   +3 more
doaj   +2 more sources

Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
There are many studies devoted to the role of hair follicle stem cells in wound healing as well as in follicle self-restoration. At the same time, the influence of the inflammatory cells on the hair follicle cycling in both injured and intact skin is ...
Elena I. Morgun, Ekaterina A. Vorotelyak
doaj   +2 more sources

Revealing the Therapeutic Potential of Stem Cells in Burn Healing: A Deeper Understanding of the Therapeutic Mechanisms of Epidermal Stem Cells and Mesenchymal Stem Cells [PDF]

open access: yesStem Cells International
Conclusion: The present study obtained deep insight into the developing trends and research hotspots on burns associated with stem cells, which arouses growing concerns and implies increasing clinical implications.
Jianyu Lu   +14 more
doaj   +2 more sources

Epidermal Stem Cells of the Skin [PDF]

open access: yesAnnual Review of Cell and Developmental Biology, 2006
The skin constantly renews itself throughout adult life, and the hair follicle undergoes a perpetual cycle of growth and degeneration. Stem cells (SCs) residing in the epidermis and hair follicle ensure the maintenance of adult skin homeostasis and hair regeneration, but they also participate in the repair of the epidermis after injuries. We summarize
Blanpain, Cédric, Fuchs, Elaine
openaire   +3 more sources

Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth

open access: yesStem Cell Research & Therapy, 2020
Millions suffer from skin diseases. Functional interfollicular epidermal stem cells are needed in skin therapy or drug screening in vitro. We obtained functional interfollicular epidermal stem cells with intact stemness and cell junctions by treating ...
Ling Leng   +6 more
doaj   +1 more source

Gremlin 2 suppresses differentiation of stem/progenitor cells in the human skin

open access: yesRegenerative Therapy, 2021
Introduction: The skin is comprised of various kinds of cells and has three layers, the epidermis, dermis and subcutaneous adipose tissue. Stem cells in each tissue duplicate themselves and differentiate to supply new cells that function in the tissue ...
Mika Kawagishi-Hotta   +7 more
doaj   +1 more source

Biochemistry of epidermal stem cells [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2013
The epidermis is an important protective barrier that is essential for maintenance of life. Maintaining this barrier requires continuous cell proliferation and differentiation. Moreover, these processes must be balanced to produce a normal epidermis. The stem cells of the epidermis reside in specific locations in the basal epidermis, hair follicle and ...
Richard L, Eckert   +7 more
openaire   +2 more sources

Hair follicle epidermal stem cells define a niche for tactile sensation

open access: yeseLife, 2018
The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive.
Chun-Chun Cheng   +13 more
doaj   +1 more source

Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells [PDF]

open access: yes, 2012
Widera D, Hauser S, Kaltschmidt C, Kaltschmidt B. Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy Research International.
Hauser, Stefan   +4 more
core   +1 more source

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