Epidermal stem cell dynamics [PDF]
Stem Cell Research & Therapy, 2011 Wong and Reiter have explored the possibility that hair follicle stem cells can give rise to basal cell carcinoma (BCC). They expressed in mice an inducible human BCC-derived oncogenic allele of Smoothened, SmoM2, under the control of either the cytokeratin 14 (K14) or cytokeratin 15 (K15) promoter.
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A positive regulatory loop between foxi3a and foxi3b is essential for specification and differentiation of zebrafish epidermal ionocytes. [PDF]
PLoS ONE, 2007 BACKGROUND: Epidermal ionocytes play essential roles in the transepithelial transportation of ions, water, and acid-base balance in fish embryos before their branchial counterparts are fully functional.
Chung-Der Hsiao +5 more
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Mechanisms regulating epidermal stem cells [PDF]
The EMBO Journal, 2012 The skin epidermis contains different appendages such as the hair follicle and the sebaceous glands. Recent studies demonstrated that several types of stem cells (SCs) exist in different niches within the epidermis and maintain discrete epidermal compartments, but the exact contribution of each SC populations under physiological conditions is still ...
Beck, Benjamin, Blanpain, Cédric
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Skin-derived stem cells for wound treatment using cultured epidermal autografts : clinical applications and challenges [PDF]
, 2018 The human skin fulfills important barrier, sensory, and immune functions—all of which contribute significantly to health and organism integrity. Widespread skin damage requires immediate treatment and coverage because massive skin loss fosters the ...
Charli Kruse +23 more
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Alp rose stem cells as cosmetic creams ingredient: Expected and established creams effects on the skin [PDF]
Arhiv za farmaciju, 2018 In the cosmetic industry, a frequent anti-aging approach is the protection of cells responsible for the continuous skin renewal and the maintenance of its barrier function - epidermal stem cells, using the secondary metabolites and epigenetic factors of ...
Filipović Mila +3 more
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Effective use of mesenchymal stem cells in human skin substitutes generated by tissue engineering [PDF]
European Cells & Materials, 2019 Mesenchymal stem cells (MSCs) can differentiate toward epithelial cells and may be used as an alternative source for generation of heterotypical artificial human skin substitutes, thus, enhancing their development and translation potential to the clinic.
MA Martin-Piedra +8 more
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eLife, 2017 The cutaneous wound-healing program is a product of a complex interplay among diverse cell types within the skin. One fundamental process that is mediated by these reciprocal interactions is the mobilization of local stem cell pools to promote tissue ...
Pedro Lee +11 more
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Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. [PDF]
PLoS ONE, 2015 In recent years, several studies have shed light into the processes that regulate epidermal specification and homeostasis. We previously showed that a broad-spectrum γ-secretase inhibitor DAPT promoted early keratinocyte specification in human embryonic ...
Ana Mafalda Baptista Tadeu +6 more
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Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]
, 2012 Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger +3 more
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Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. [PDF]
PLoS ONE, 2013 Epidermal squamous cell carcinoma is among the most common cancers in humans. These tumors are comprised of phenotypically diverse populations of cells that display varying potential for proliferation and differentiation. An important goal is identifying
Gautam Adhikary +11 more
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