Results 61 to 70 of about 5,134,709 (287)
JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
Nature Communications, 2018 Epidermal homeostasis is maintained by the activity of stem cells. Here, the authors show that deficiency of the transcription factor JunB leads to altered Notch signaling in stem cells, resulting in a cell fate switch and de novo formation of aberrant ...
Karmveer Singh +13 more
doaj +1 more source
Dataset on gene expression profiling of multiple murine hair follicle populations
Data in Brief, 2016 The murine hair follicle contains several different keratinocyte progenitor populations within its compartments. By using antibodies against CD34, Itgα6, Sca-1 and Plet-1, we have isolated eight populations and compared their Krt10 and Krt14 expressions ...
Anders Patrik Gunnarsson +3 more
doaj +1 more source
Caracterização do folículo piloso como nicho de células progenitoras neurais e epidermais em camundongos [PDF]
, 2011 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2011Células tronco são células com capacidade de auto renovação, e de ...
Pereira, Ricardo Mueller Cesario
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2012 Background and Objective: Epidermis is the outer layer of skin, regenerating continuously. Epidermal stem cells play important roles in tissue regeneration, scar regeneration and neoplasm formation.This study was displayed for the isolation and culture ...
Sheikhani N (BSc) +2 more
doaj
Stem Cell Reports, 2014 We report a long-term follow-up (6.5 years) of a phase I/II clinical trial envisaging the use of autologous genetically modified cultured epidermal stem cells for gene therapy of junctional epidermolysis bullosa, a devastating genetic skin disease.
Laura De Rosa +10 more
doaj +1 more source
Niche interactions in epidermal stem cells
World Journal of Stem Cells, 2015 Within the epidermis and dermis of the skin, cells secrete and are surrounded by the extracellular matrix (ECM), which provides structural and biochemical support. The ECM of the epidermis is the basement membrane, and collagen and other dermal components constitute the ECM of the dermis.
Hye-Ryung, Choi +3 more
openaire +2 more sources
Multi‐tasking epidermal stem cells: Beyond epidermal maintenance [PDF]
Development, Growth & Differentiation, 2018 Over the past decade, multiple stem cell compartments have been identified within the epidermis. These stem cell pools have different transcriptional properties, proliferative modes and anatomical locations, and they maintain distinct epidermal compartments.
Hironobu Fujiwara +2 more
openaire +2 more sources
The in vitro plasticity of hair follicle dermal and mesenchymal stem cells [PDF]
, 2008 Stem cells from the hair follicle are an easily accessible population of cells that have a broad in vitro developmental capabilities and potential for autologous replacement of damaged adult tissue.
Emmerson, Robert
core
Purification of Immature Neuronal Cells from Neural Stem Cell Progeny [PDF]
Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications.
Brent A Reynolds +27 more
core +2 more sources