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Epigallocatechin-3-Gallate as a Novel Vaccine Adjuvant [PDF]
Frontiers in Immunology, 2021 Vaccine adjuvants from natural resources have been utilized for enhancing vaccine efficacy against infectious diseases. This study examined the potential use of catechins, polyphenolic materials derived from green tea, as adjuvants for subunit and inactivated vaccines.
Yucheol Cheong +13 more
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Epigallocatechin-3-gallate (EGCG): Chemical and biomedical perspectives [PDF]
Phytochemistry, 2006 The compound (-)-epigallocatechin-3-gallate (EGCG) is the major catechin found in green tea [Camellia sinensis L. Ktze. (Theaceae)]. This polyphenolic compound and several related catechins are believed to be responsible for the health benefits associated with the consumption of green tea.
Dale G, Nagle +2 more
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Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG) [PDF]
Nutrition Journal, 2015 Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) enforce an overwhelming social and economic burden on society. They are primarily characterized through the accumulation of modified proteins, which further trigger biological responses such as inflammation, oxidative stress, excitotoxicity and modulation of ...
Singh, Neha Atulkumar +2 more
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Computational DNA binding studies of (–)-epigallocatechin-3-gallate [PDF]
Journal of Biomolecular Structure and Dynamics, 2017 The catechin family of molecules that are present in the leaves of green tea has been under investigation since the antioxidant and anti-inflammatory properties of tea were discovered. Among multiple proposed therapeutic targets of these molecules, the direct interaction with nucleic acids has been proposed and experimentally observed but without clear
Rodrigo Galindo-Murillo +1 more
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Antifibrotic properties of epigallocatechin-3-gallate in endometriosis [PDF]
Human Reproduction, 2014 Is epigallocatechin-3-gallate (EGCG) treatment effective in the treatment of fibrosis in endometriosis?EGCG appears to have antifibrotic properties in endometriosis.Histologically, endometriosis is characterized by dense fibrous tissue surrounding the endometrial glands and stroma.
Sachiko, Matsuzaki, Claude, Darcha
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(−)-Epigallocatechin-3-gallate Is a Novel Hsp90 Inhibitor [PDF]
Biochemistry, 2008 (-)-Epigallocatechin-3-gallate (EGCG), a major component of green tea, protects against certain types of cancers, although the mechanism has not yet been determined. It was previously demonstrated that EGCG blocks aryl hydrocarbon receptor (AhR)-mediated transcription induced by the potent carcinogen 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Zhengyu, Yin +2 more
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TLC separation of methylated (-)-epigallocatechin-3-gallate [PDF]
Czech Journal of Food Sciences, 2005 Methylated EGCG was separated from the crude extract using Sephadex LH-20 column chromatography with methanol as the mobile phase, and a semi-preparative HPLC method with water-dimethylformamide-methanol-acetic acid (157:40:2:1, v/v/v/v) as the mobile phase.
Ryszard Amarowicz +2 more
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Inhibitory Effects of (−)-Epigallocatechin-3-gallate on Esophageal Cancer [PDF]
Molecules, 2019 There is epidemiological evidence showing that drinking green tea can lower the risk of esophageal cancer (EC). The effect is mainly attributed to tea polyphenols and their most abundant component, (−)-epigallocatechin-3-gallate (EGCG). The possible mechanisms of tumorigenesis inhibition of EGCG include its suppressive effects on cancer cell ...
Liu-Xiang Wang +9 more
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Green Tea Extracts Epigallocatechin-3-gallate for Different Treatments [PDF]
BioMed Research International, 2017 Epigallocatechin-3-gallate (EGCG), a component extracted from green tea, has been proved to have multiple effects on human pathological and physiological processes, and its mechanisms are discrepant in cancer, vascularity, bone regeneration, and nervous system.
Chenyu Chu, Jia Deng, Yi Man, Yili Qu
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Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells
OncoTargets and Therapy, 2016 Epigallocatechin-3-gallate (EGCG) is an antioxidant agent derived from green tea. Because it has chemopreventive and anti-invasive effect against various cancer cells, EGCG can be used to inhibit proliferation and invasion of cholangiocarcinoma (CCA) cells.The anticancer effects of EGCG were studied using human CCA cells (HuCC-T1).
Kwak, Tae Won +4 more
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