Results 61 to 70 of about 208,229 (162)

Epigenetic aging in oocytes

Aging, 2023
Wasserzug-Pash, Peera, Klutstein, Michael   +1 more
openaire   +2 more sources

Association of blood cadmium levels with epigenetic age acceleration in U.S. adults aged > 50 years

Frontiers in Public Health
ObjectivesDNA methylation (DNAm) is a sensitive biomarker of aging-related processes, and novel epigenetic-based “clocks” can estimate accelerated biological aging.
Panpan Mi, Xu Cao, Haixia Feng, Huijie Wang   +3 more
doaj   +1 more source

Epigenetic chaperoning of aging [PDF]

Aging, 2020
Müthel, S., Tursun, B.
openaire   +2 more sources

Cytomegalovirus infection accelerates epigenetic aging

Experimental Gerontology, 2015
Epigenetic mechanisms such as DNA methylation (DNAm) have a central role in the regulation of gene expression and thereby in cellular differentiation and tissue homeostasis. It has recently been shown that aging is associated with profound changes in DNAm. Several of these methylation changes take place in a clock-like fashion, i.e.
Jylhava Juulia, Kananen Laura, Jylha Marja, Marttila Saara, Nevalainen Tapio, Hervonen Antti, Hurme Mikko, Hurme Mikko   +7 more
openaire   +2 more sources

Genome-wide methylation biomarkers and biological aging in patients with bipolar disorder characterized for lithium response

European Psychiatry
Background Epigenetic mechanisms might play a role in modulating susceptibility to bipolar disorder (BD) and response to lithium, the mainstay treatment for BD. Additionally, individuals with BD experience accelerated biological aging.
Claudia Pisanu, Alessandra Minelli, Donatella Congiu, Anna Meloni, Pasquale Paribello, Lisa Buson, Caterina Chilllotti, Marco Bortolomasi, Raffaella Ardau, Massimo Gennarelli, Giovanni Severino, Federica Pinna, Marco Pinna, Martina Contu, Maria Del Zompo, Bernardo Carpiniello, Mirko Manchia, Alessio Squassina   +17 more
doaj   +1 more source

Human epigenetic ageing is logarithmic with time across the entire lifespan

Epigenetics, 2019
Epigenetic changes during ageing have been characterized by multiple epigenetic clocks that allow the prediction of chronological age based on methylation status.
Sagi Snir, Colin Farrell, Matteo Pellegrini   +2 more
doaj   +1 more source

Heavy metals, epigenetic aging, and mortality: A cohort study

Ecotoxicology and Environmental Safety
Background: Aging is a multifaceted biological process modulated by interplay of genetic determinants and environmental influences. However, the role of epigenetic aging in the association between environmental exposures and mortality risk in human ...
Hua Wang, Yunyun Liu, Shuxiang Yan, Chenbei Li, Jinxin Tang, Hongkun Hu, Mingyang Wu, Chao Tu   +7 more
doaj   +1 more source

Epigenetic Aging in Osteoporosis [PDF]

Journal of Bone and Mineral Research, 2018
Alvaro, Del Real, Leyre, Riancho-Zarrabeitia, Jose A, Riancho   +2 more
openaire   +2 more sources

Causal Associations of Epigenetic Age Acceleration With Stroke and Its Functional Outcome: A Two‐Sample, Two‐Step Mendelian Randomization Study

Brain and Behavior
Background Emerging evidence from observational studies suggested that epigenetic age acceleration may result in an increased incidence of stroke and poorer functional outcomes after a stroke.
Baizhi Qiu, Shuyang Wen, Zifan Li, Yuxin Cai, Qi Zhang, Yuting Zeng, Shuqi Zheng, Zhishan Lin, Yupeng Xiao, Jihua Zou, Guozhi Huang, Qing Zeng   +11 more
doaj   +1 more source

The relationship between epigenetic biomarkers and the risk of diabetes and cancer: a machine learning modeling approach

Frontiers in Public Health
IntroductionEpigenetic biomarkers are molecular indicators of epigenetic changes, and some studies have suggested that these biomarkers have predictive power for disease risk.
Shiqi Zhang, Shiqi Zhang, Jianan Jin, Benfeng Xu, Qi Zheng, Haibo Mou   +5 more
doaj   +1 more source