Results 41 to 50 of about 5,479,707 (298)
Epigenetics, 2022 Maternal pregnancy fatty acid status is associated with child health. Epigenetic gestational age acceleration, referring to a discrepancy between chronological and epigenetic gestational age, may underlie these associations.
Giulietta S. Monasso +2 more
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Epigenetic Control of Aging [PDF]
Antioxidants & Redox Signaling, 2011 Organismal aging and longevity are influenced by many complex interacting factors. Epigenetics has recently emerged as another possible determinant of aging. Here, we review some of the epigenetic pathways that contribute to cellular senescence and age-associated phenotypes.
Ursula, Muñoz-Najar, John M, Sedivy
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Epigenetic Clocks and Programmatic Aging
Ageing Research Reviews, 2023 The last decade has seen remarkable progress in the characterization of methylation clocks that track biological age in humans and many other mammalian species. While the biological processes of aging that underlie these clocks have remained unclear, several clues have pointed to a link to developmental mechanisms.
David Gems +2 more
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Epigenetics, 2021 Previous studies suggest epigenetic alterations may contribute to the association between maternal prenatal depression and adverse offspring outcomes. Developmental researchers have recently begun to examine these associations in relation to epigenetic ...
Brooke G. McKenna +6 more
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Aging as an Epigenetic Phenomenon [PDF]
Current Genomics, 2017 Hypermethylation of genes associated with promoter CpG islands, and hypomethylation of CpG poor genes, repeat sequences, transposable elements and intergenic genome sections occur during aging in mammals. Methylation levels of certain CpG sites display strict correlation to age and could be used as "epigenetic clock" to predict biological age.
Ashapkin, Vasily V. +2 more
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Epigenetic aging of mammalian gametes
Molecular Reproduction and Development, 2023 AbstractThe process of aging refers to physiological changes that occur to an organism as time progresses and involves changes to DNA, proteins, metabolism, cells, and organs. Like the rest of the cells in the body, gametes age, and it is well established that there is a decline in reproductive capabilities in females and males with aging.
Michael Klutstein, Nitzan Gonen
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Infectious exposures and epigenetic age
, 2022 Analysis of associations between infections exposures in infancy and epigenetic age in a cohort of young adults in Cebu ...
Thomas McDade
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Epigenetic age estimation of cetaceans [PDF]
, 2021 Age is an important biological parameter which can be used to guide conservation. It is difficult to assess in wild populations, however, and especially in many cetacean species. Epigenetic analyses now offer an alternative for age estimation.
Matthew James Heydenrych (23513614)
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Inverse relationship between genetic diversity and epigenetic complexity [PDF]
, 2008 Early studies of molecular evolution revealed a correlation between genetic distance and time of species divergence. This observation provoked the molecular clock hypothesis and in turn the ‘Neutral Theory’, which however remains an ...
Shi Huang
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EPIGENETIC AGING AND RHEUMATOID ARTHRITIS
Innovation in Aging, 2023 Abstract Indicators of biological aging with rheumatoid arthritis (RA), a chronic autoimmune disease, are not yet fully known. In this cross-sectional study, we tested associations between plasma indicators of epigenetic aging using online data (GSE42861) regarding RA and DNA methylation from the Swedish Epidemiological Investigation of ...
Nandini Mukherjee, Tracie C Harrison
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