Epigenetic clock analysis of blood samples in drug-naive first-episode schizophrenia patients [PDF]
BMC Psychiatry, 2023 Background Schizophrenia (SCZ) is a severe and chronic psychiatric disorder with premature age-related physiological changes. However, numerous previous studies examined the epigenetic age acceleration in SCZ patients and yielded inconclusive results. In
Zongchang Li +6 more
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Epigenetic Clock: DNA Methylation in Aging [PDF]
Stem Cells International, 2020 Aging, which is accompanied by decreased organ function and increased disease incidence, limits human lifespan and has attracted investigators for thousands of years.
Shuang Jiang, Yuchen Guo
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Epigenetic clock and methylation studies in cats. [PDF]
Geroscience, 2021 Abstract Human DNA methylation profiles have been used successfully to develop highly accurate biomarkers of aging (“epigenetic clocks”). Although these human epigenetic clocks are not immediately applicable to all species of the animal kingdom, the principles underpinning them appear to be conserved even in ...
Raj K +8 more
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Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men [PDF]
Frontiers in Neuroscience, 2021 Epigenetic clocks are among the most promising biomarkers of aging. It is particularly important to establish biomarkers of brain aging to better understand neurodegenerative diseases.
Francine Grodstein +8 more
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A Targeted Epigenetic Clock for the Prediction of Biological Age [PDF]
Cells, 2022 Epigenetic clocks were initially developed to track chronological age, but accumulating evidence indicates that they can also predict biological age.
Noémie Gensous +17 more
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Development of an epigenetic clock to predict visual age progression of human skin [PDF]
Frontiers in Aging, 2023 Aging is a complex process characterized by the gradual decline of physiological functions, leading to increased vulnerability to age-related diseases and reduced quality of life.
Agata Bienkowska +11 more
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Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes [PDF]
Advanced ScienceEpigenetic clocks in blood have shown promise as tools to quantify biological age, displaying robust associations with morbidity and all‐cause mortality.
Xiaolong Guo +17 more
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Influence of physical activity on the epigenetic clock: evidence from a Japanese cross-sectional study [PDF]
Clinical EpigeneticsBackground Biological age, especially epigenetic age derived from the epigenetic clock, is a significant measure of aging, considering the differences in aging rates among individuals.
Masatoshi Nagata +6 more
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Epigenetics, 2018 Horvath’s epigenetic clock consists of 353 CpGs whose methylation levels can accurately predict the age of individuals. Using bioinformatics analysis, we investigated the conformation, energy characteristics and presence of tentative splice sites of the ...
Andigoni Malousi +5 more
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Accelerated epigenetic clock aging in maternal peripheral blood and preterm birth. [PDF]
Am J Obstet Gynecol, 2023 Gascoigne EL +4 more
europepmc +3 more sources