Results 11 to 20 of about 14,428 (154)
An epigenetic clock for human skeletal muscle [PDF]
Journal of Cachexia, Sarcopenia and Muscle, 2020 Background Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues.
Sarah Voisin +15 more
doaj +7 more sources
Calibrating epigenetic clocks with training data error
Evolutionary Applications, 2023 Animal age data are valuable for management of wildlife populations. Yet, for most species, there is no practical method for determining the age of unknown individuals.
Benjamin Mayne +2 more
doaj +3 more sources
Developmental Tuning of Epigenetic Clock [PDF]
Frontiers in Genetics, 2018 Research in the field of gerontology has traditionally focused on later life stages. There is increasing evidence, however, that both the rate of age-related functional decline and the later-life health status can be programmed during early development ...
Alexander Vaiserman
doaj +3 more sources
Epigenetic Clock: DNA Methylation in Aging [PDF]
Stem Cells International, 2020 Aging, which is accompanied by decreased organ function and increased disease incidence, limits human lifespan and has attracted investigators for thousands of years.
Shuang Jiang, Yuchen Guo
doaj +4 more sources
An epigenetic clock for Xenopus tropicalis. [PDF]
NPJ AgingAbstract DNA methylation clocks have been widely used for accurate age prediction, but most studies have been carried out on mammals. Here we present an epigenetic clock for the aquatic frog Xenopus tropicalis, a widely used model organism in developmental biology and genomics.
Bennett R +4 more
europepmc +3 more sources
Epigenetic Clocks and Programmatic Aging
Ageing Research Reviews, 2023 The last decade has seen remarkable progress in the characterization of methylation clocks that track biological age in humans and many other mammalian species. While the biological processes of aging that underlie these clocks have remained unclear, several clues have pointed to a link to developmental mechanisms.
David Gems +2 more
openaire +2 more sources
Circadian clocks, epigenetics, and cancer [PDF]
Current Opinion in Oncology, 2015 The interplay between circadian rhythm and cancer has been suggested for more than a decade based on the observations that shift work and cancer incidence are linked. Accumulating evidence implicates the circadian clock in cancer survival and proliferation pathways.
Masri, Selma +2 more
openaire +4 more sources
Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men
Frontiers in Neuroscience, 2021 Epigenetic clocks are among the most promising biomarkers of aging. It is particularly important to establish biomarkers of brain aging to better understand neurodegenerative diseases.
Francine Grodstein +8 more
doaj +1 more source
Cardiovascular health and four epigenetic clocks
Clinical Epigenetics, 2022 Abstract Background Cardiovascular health (CVH) was defined by the American Heart Association as an integrative idealness of seven clinical or lifestyle factors. Based on populations of European ancestry, recent studies have shown that ideal CVH is associated with a slower aging rate. The aging rate is measured by levels
Yun-Hsiang Lo, Wan-Yu Lin
openaire +2 more sources
Scientific Reports, 2023 Age structure information of animal populations is fundamental to their conservation and management. In fisheries, age is routinely obtained by counting daily or annual increments in calcified structures (e.g., otoliths) which requires lethal sampling ...
Benjamin Mayne +11 more
doaj +1 more source