Results 21 to 30 of about 14,860 (271)
Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids
Communications Biology, 2021 Larison et al. report epigenetic aging models in plains zebras (Equus quagga) using the epigenetic clock and epigenetic pacemaker approaches. Their epigenetic clock allows age to be accurately estimated in endangered sister species, and the pacemaker ...
Brenda Larison +13 more
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Neurobiology of Stress, 2021 Background: Studies reporting accelerated ageing in children with affective disorders or maltreatment exposure have relied on algorithms for estimating epigenetic age derived from adult samples.
Felix Dammering +11 more
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Evaluation of pediatric epigenetic clocks across multiple tissues
Clinical Epigenetics, 2023 Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang +28 more
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An Epigenetic Aging Clock for Cattle Using Portable Sequencing Technology
Frontiers in Genetics, 2021 Extensively grazed cattle are often mustered only once a year. Therefore, birthdates are typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management
Ben J. Hayes +7 more
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Circadian clocks, epigenetics, and cancer [PDF]
Current Opinion in Oncology, 2015 The interplay between circadian rhythm and cancer has been suggested for more than a decade based on the observations that shift work and cancer incidence are linked. Accumulating evidence implicates the circadian clock in cancer survival and proliferation pathways.
Masri, Selma +2 more
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Dynamic epigenetic age mosaicism in the human atherosclerotic artery
PLoS ONE, 2022 Accelerated epigenetic ageing, a promising marker of disease risk, has been detected in peripheral blood cells of atherosclerotic patients, but evidence in the vascular wall is lacking.
Silvio Zaina +3 more
doaj +3 more sources
Scientific Reports, 2023 Age structure information of animal populations is fundamental to their conservation and management. In fisheries, age is routinely obtained by counting daily or annual increments in calcified structures (e.g., otoliths) which requires lethal sampling ...
Benjamin Mayne +11 more
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Cardiovascular health and four epigenetic clocks
Clinical Epigenetics, 2022 Abstract Background Cardiovascular health (CVH) was defined by the American Heart Association as an integrative idealness of seven clinical or lifestyle factors. Based on populations of European ancestry, recent studies have shown that ideal CVH is associated with a slower aging rate. The aging rate is measured by levels
Yun-Hsiang Lo, Wan-Yu Lin
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Nature Communications, 2022 The temporal development of tissues and organs may be defined by the genome-wide epigenetic and transcriptional state functioning as the clock. Here the authors found that Fbl, a ribosomal RNA methyltransferase, potentially behaves as a clock during ...
Quan Wu +7 more
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An epigenetic clock controls aging [PDF]
Biogerontology, 2015 We are accustomed to treating aging as a set of things that go wrong with the body. But for more than twenty years, there has been accumulating evidence that much of the process takes place under genetic control. We have seen that signaling chemistry can make dramatic differences in life span, and that single molecules can significantly affect ...
Josh Mitteldorf
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