Results 11 to 20 of about 193,396 (281)
Evaluation of pediatric epigenetic clocks across multiple tissues [PDF]
Clinical Epigenetics, 2023 Background Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.
Fang Fang +28 more
doaj +6 more sources
Transfer Elastic Net for Developing Epigenetic Clocks for the Japanese Population
MathematicsThe epigenetic clock evaluates human biological age based on DNA methylation patterns. It takes the form of a regression model where the methylation ratio at CpG sites serves as the predictor and age as the response variable.
Yui Tomo, Ryo Nakaki
doaj +2 more sources
Assessing the utility of epigenetic clocks for health prediction in South Korean [PDF]
Frontiers in AgingEpigenetic clocks have been developed to track both chronological age and biological age, which is defined by physiological biomarkers and the risk of adverse health outcomes.
Dong Jun Kim +6 more
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Epigenetic Clocks: Biological Aging, Disease, and Clinical Applications
The EuroBiotech JournalEpigenetic clocks are DNA methylation-based models that estimate biological age and provide a quantitative framework for investigating interindividual differences in aging.
Baki Yildirim A. +12 more
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Epigenetic aging clocks in mice and men
Genome Biology, 2017 Genome biology 18(1), 107 (2017).
Wagner, Wolfgang, Wolfgang Wagner
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Epigenetic clocks are not accelerated in COVID-19 patients [PDF]
International Journal of Molecular Sciences, 2020 Abstract Age is a major risk factor for severe outcome of coronavirus disease 2019 (COVID-19), but it remains unclear if this is rather due to increased chronological age or biological age. During lifetime, specific DNA methylation changes are acquired in our genome that act as “epigenetic clocks” allowing to estimate donor age and to ...
Julia Franzen +12 more
openaire +5 more sources
Epigenetic clocks in relapse after a first episode of schizophrenia [PDF]
, 2022 The main objective of the present study was to investigate the association between several epigenetic clocks, covering different aspects of aging, with schizophrenia relapse evaluated over a 3-year follow-up period in a cohort of ninety-one first-episode
Judit Selma +103 more
core +4 more sources
Clinical EpigeneticsBackground Human aging and white blood cell (WBC) count are complex traits influenced by multiple genetic factors. Predictors of chronological age have been developed using epigenetic clocks.
Manli Sun +8 more
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Epigenetic clocks in the pediatric population: when and why they tick?
Chinese Medical Journal, 2021 . Recent research efforts have provided compelling evidence of genome-wide DNA methylation alterations in pediatrics. It is currently well established that epigenetic clocks, composed of DNA methylation sites, can estimate the gestational and ...
Jing Wang, Wen-Hao Zhou, Jing Ni
doaj +1 more source
Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men
Frontiers in Neuroscience, 2021 Epigenetic clocks are among the most promising biomarkers of aging. It is particularly important to establish biomarkers of brain aging to better understand neurodegenerative diseases.
Francine Grodstein +8 more
doaj +1 more source