Results 1 to 10 of about 306,895 (150)

Systematic analysis of JmjC gene family and stress­-response expression of KDM5 subfamily genes in Brassica napus [PDF]

PeerJ, 2021
Background Jumonji C (JmjC) proteins exert critical roles in plant development and stress response through the removal of lysine methylation from histones.
Xinghui He, Qianwen Wang, Jiao Pan, Boyu Liu, Ying Ruan, Yong Huang   +5 more
doaj   +2 more sources

Dynamics of Whole-Genome Contacts of Nucleoli in Drosophila Cells Suggests a Role for rDNA Genes in Global Epigenetic Regulation

Cells, 2020
Chromosomes are organized into 3D structures that are important for the regulation of gene expression and differentiation. Important role in formation of inter-chromosome contacts play rDNA clusters that make up nucleoli. In the course of differentiation,
Nickolai A. Tchurikov, Elena S. Klushevskaya, Daria M. Fedoseeva, Ildar R. Alembekov, Galina I. Kravatskaya, Vladimir R. Chechetkin, Yuri V. Kravatsky, Olga V. Kretova   +7 more
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Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

Genome Biology, 2021
Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon, Adrian Janiszewski, Bart Theeuwes, Thomas Lefevre, Juan Song, Greet Bervoets, Lotte Vanheer, Natalie De Geest, Suresh Poovathingal, Ryan Allsop, Jean-Christophe Marine, Florian Rambow, Thierry Voet, Vincent Pasque   +13 more
doaj   +1 more source

LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation

Nature Communications, 2023
Glioblastoma (GBM) ranks among the most lethal of human cancers, containing glioma stem cells (GSCs) that display therapeutic resistance. Here, we report that the lncRNA INHEG is highly expressed in GSCs compared to differentiated glioma cells (DGCs) and
Lihui Liu, Ziyang Liu, Qinghua Liu, Wei Wu, Peng Lin, Xing Liu, Yuechuan Zhang, Dongpeng Wang, Briana C. Prager, Ryan C. Gimple, Jichuan Yu, Weixi Zhao, Qiulian Wu, Wei Zhang, Erzhong Wu, Xiaomin Chen, Jianjun Luo, Jeremy N. Rich, Qi Xie, Tao Jiang, Runsheng Chen   +20 more
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Lipid droplets are formed in 2-cell-like cells

The Journal of Reproduction and Development, 2021
Embryonic stem (ES) cells, derived from the inner cell mass of a blastocyst, are believed to pluripotent cells and give rise to embryonic, but not extraembryonic, tissues.
Asuka FURUTA, Toshinobu NAKAMURA
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rDNA Clusters Make Contact with Genes that Are Involved in Differentiation and Cancer and Change Contacts after Heat Shock Treatment

Cells, 2019
Human rDNA clusters form numerous contacts with different chromosomal regions as evidenced by chromosome conformation capture data. Heterochromatization of rDNA genes leads to heterochromatization in different chromosomal regions coupled with the ...
Nickolai A. Tchurikov, Daria M. Fedoseeva, Elena S. Klushevskaya, Ivan Y. Slovohotov, Vladimir R. Chechetkin, Yuri V. Kravatsky, Olga V. Kretova   +6 more
doaj   +1 more source

Evolution and conservation of polycomb repressive complex 1 core components and putative associated factors in the green lineage

BMC Genomics, 2019
Background Polycomb group (PcG) proteins play important roles in animal and plant development and stress response. Polycomb repressive complex 1 (PRC1) and PRC2 are the key epigenetic regulators of gene expression, and are involved in almost all ...
Yong Huang, Ling Jiang, Bo-Yu Liu, Cheng-Fang Tan, Dong-Hong Chen, Wen-Hui Shen, Ying Ruan   +6 more
doaj   +1 more source

SDG26 Is Involved in Trichome Control in Arabidopsis thaliana: Affecting Phytohormones and Adjusting Accumulation of H3K27me3 on Genes Related to Trichome Growth and Development

Plants, 2023
Plant trichomes formed by specialized epidermal cells play a role in protecting plants from biotic and abiotic stresses and can also influence the economic and ornamental value of plant products.
Jing Zeng, Lanpeng Yang, Minyu Tian, Xiang Xie, Chunlin Liu, Ying Ruan   +5 more
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Comprehensive mapping of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions

Nature Communications, 2021
Here, Yang et al. apply different RNA sequencing approaches to characterize the secondary structure of SARS-CoV-2 viral RNAs, report on long-range interactions along the viral genome, and uncover the virus-host RNA interactome in cells.
Siwy Ling Yang, Louis DeFalco, Danielle E. Anderson, Yu Zhang, Jong Ghut Ashley Aw, Su Ying Lim, Xin Ni Lim, Kiat Yee Tan, Tong Zhang, Tanu Chawla, Yan Su, Alexander Lezhava, Andres Merits, Lin-Fa Wang, Roland G. Huber, Yue Wan   +15 more
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Six Highly Conserved Targets of RNAi Revealed in HIV-1-Infected Patients from Russia Are Also Present in Many HIV-1 Strains Worldwide

Molecular Therapy: Nucleic Acids, 2017
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets.
Olga V. Kretova, Daria M. Fedoseeva, Maria A. Gorbacheva, Natalya M. Gashnikova, Maria P. Gashnikova, Nataliya V. Melnikova, Vladimir R. Chechetkin, Yuri V. Kravatsky, Nickolai A. Tchurikov   +8 more
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