Results 151 to 160 of about 86,342 (328)
Molecular Nutrition &Food Research, EarlyView.Over half of patients with colorectal cancer experience severe chemotherapy‐induced side effects. The B‐vitamin folate may play a role in these side effects, potentially by altering DNA methylation, a mechanism of gene regulation. Our comprehensive literature search identified studies investigating DNA methylation associated with folate status/intake ...
Nienke R. K. Zwart +3 more
wiley +1 more source
Aging Cell, EarlyView.Injury then recovery markedly rewires the DNA methylome in aged skeletal muscle.The addition of senolytics during muscle regeneration decelerates DNAmAGE more than regeneration alone as well as targets collagen remodeling and stem cell function‐related genes.
Toby L. Chambers +16 more
wiley +1 more source
Applications of Novel Techniques to Health Foods, Medical and Agricultural Biotechnology [PDF]
arXiv, 2004 Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new niches for Biotechnology and prevent the shrinking or closing the existing ones.
arxiv
Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma [PDF]
, 2019 BACKGROUND: Treatment for Cutaneous T Cell Lymphoma (CTCL) is generally not curative. Therefore, selecting therapy that is effective and tolerable is critical to clinical decision-making. Histone deacetylase inhibitors (HDACi), epigenetic modifier drugs,
Andrews, Jared M +5 more
core +2 more sources
Aging Cell, EarlyView.Therapeutic plasma exchange safely reduces biological age by up to 2.6 years. Multi‐omics analysis reveals coordinated cellular and molecular responses associated with aging rejuvenation. ABSTRACT We conducted a randomized, placebo‐controlled trial to assess the safety and biological age (BA) effects of various therapeutic plasma exchange (TPE ...
Matias Fuentealba +14 more
wiley +1 more source
Integrative clustering of high-dimensional data with joint and individual clusters, with an application to the Metabric study [PDF]
arXiv, 2014 When measuring a range of different genomic, epigenomic, transcriptomic and other variables, an integrative approach to analysis can strengthen inference and give new insights. This is also the case when clustering patient samples, and several integrative cluster procedures have been proposed.
arxiv
Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats
Aging Cell, EarlyView.Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura +15 more
wiley +1 more source
Spectral Learning of Large Structured HMMs for Comparative Epigenomics [PDF]
arXiv, 2015 We develop a latent variable model and an efficient spectral algorithm motivated by the recent emergence of very large data sets of chromatin marks from multiple human cell types. A natural model for chromatin data in one cell type is a Hidden Markov Model (HMM); we model the relationship between multiple cell types by connecting their hidden states by
arxiv
Beyond DNA: Epigenetics and Proteomics in Forensic Science [PDF]
, 2016 The use of genetic evidence in criminal cases is well established and has improved the public opinion and credibility of forensic science. However, several shortcomings associated with current genetic profiling techniques exist. Scientific research aimed
Eilerts, Diane F
core +1 more source
Semirandom Sampling to Detect Differentiation-Related and Age-Related Epigenome Remodeling [PDF]
, 2004 Valya Russanova +2 more
openalex +1 more source