Results 151 to 160 of about 87,804 (313)

SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes [PDF]

open access: gold, 2008
Raj Chari   +8 more
openalex   +1 more source

Predicting the Future: Parental Progeny Investment in Response to Environmental Stress Cues [PDF]

open access: yes, 2019
Environmental stressors can severely limit the ability of an organism to reproduce as lifespan is decreased and resources are shifted away from reproduction to survival.
Gulyas, Leah, Powell, Jennifer R.
core   +1 more source

Integrative Multiparametric Analysis of Circulating Cell‐Free Nucleic Acids of Plasma in Healthy Individuals During Aging

open access: yesAging Cell, EarlyView.
We performed the first integrative multiparametric analysis of plasma circulating cell‐free nucleic acids, including nuclear and mitochondrial DNA, as well as ribosomal, messenger, and micro‐RNAs, in a cohort of 139 healthy individuals. We focused on quantity, integrity, and DNA methylation using assays targeting highly repetitive DNA and highly ...
Nicolas P. Tessier   +10 more
wiley   +1 more source

MskAge—An Epigenetic Biomarker of Musculoskeletal Age Derived From a Genetic Algorithm Islands Model

open access: yesAging Cell, EarlyView.
Created in BioRender. Laird, E. (2025) https://BioRender.com/bqfajrn. ABSTRACT Age is a significant risk factor for functional decline and disease of the musculoskeletal system, yet few biomarkers exist to facilitate ageing research in musculoskeletal tissues. Multivariate models based on DNA methylation, termed epigenetic clocks, have shown promise as
Daniel C. Green   +8 more
wiley   +1 more source

CRISPR-based epigenome editing of cytokine receptors for the promotion of cell survival and tissue deposition in inflammatory environments [PDF]

open access: yes, 2017
Bowles, Robby D   +8 more
core   +2 more sources

DNA methylation associated with postpartum depressive symptoms overlaps findings from a genome-wide association meta-analysis of depression [PDF]

open access: yes, 2019
Background Perinatal depressive symptoms have been linked to adverse maternal and infant health outcomes. The etiology associated with perinatal depressive psychopathology is poorly understood, but accumulating evidence suggests that understanding inter ...
Kinser, Patricia A.   +5 more
core   +1 more source

Epigenetic Age Monitoring in Professional Soccer Players for Tracking Recovery and the Effects of Strenuous Exercise

open access: yesAging Cell, EarlyView.
Strenuous exercise affects biological aging in professional soccer players. DNA methylation markers analyzed from saliva samples showed epigenetic rejuvenation of the players after soccer games. Furthermore, analyses within the early recovery phase of athletes suggest a potential link between epigenetic markers and injury risk. Our study highlights the
Robert T. Brooke   +12 more
wiley   +1 more source

Epigenomics in cancer management

open access: yesCancer Management and Research, 2010
The identification of all epigenetic modifications implicated in gene expression is the next step for a better understanding of human biology in both normal and pathological states. This field is referred to as epigenomics, and it is defined as epigenetic changes (ie, DNA methylation, histone modifications and regulation by noncoding RNAs such as ...
openaire   +6 more sources

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