Results 151 to 160 of about 87,804 (313)
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes [PDF]
Raj Chari+8 more
openalex +1 more source
Predicting the Future: Parental Progeny Investment in Response to Environmental Stress Cues [PDF]
Environmental stressors can severely limit the ability of an organism to reproduce as lifespan is decreased and resources are shifted away from reproduction to survival.
Gulyas, Leah, Powell, Jennifer R.
core +1 more source
We performed the first integrative multiparametric analysis of plasma circulating cell‐free nucleic acids, including nuclear and mitochondrial DNA, as well as ribosomal, messenger, and micro‐RNAs, in a cohort of 139 healthy individuals. We focused on quantity, integrity, and DNA methylation using assays targeting highly repetitive DNA and highly ...
Nicolas P. Tessier+10 more
wiley +1 more source
MskAge—An Epigenetic Biomarker of Musculoskeletal Age Derived From a Genetic Algorithm Islands Model
Created in BioRender. Laird, E. (2025) https://BioRender.com/bqfajrn. ABSTRACT Age is a significant risk factor for functional decline and disease of the musculoskeletal system, yet few biomarkers exist to facilitate ageing research in musculoskeletal tissues. Multivariate models based on DNA methylation, termed epigenetic clocks, have shown promise as
Daniel C. Green+8 more
wiley +1 more source
CRISPR-based epigenome editing of cytokine receptors for the promotion of cell survival and tissue deposition in inflammatory environments [PDF]
Bowles, Robby D+8 more
core +2 more sources
DNA methylation associated with postpartum depressive symptoms overlaps findings from a genome-wide association meta-analysis of depression [PDF]
Background Perinatal depressive symptoms have been linked to adverse maternal and infant health outcomes. The etiology associated with perinatal depressive psychopathology is poorly understood, but accumulating evidence suggests that understanding inter ...
Kinser, Patricia A.+5 more
core +1 more source
Strenuous exercise affects biological aging in professional soccer players. DNA methylation markers analyzed from saliva samples showed epigenetic rejuvenation of the players after soccer games. Furthermore, analyses within the early recovery phase of athletes suggest a potential link between epigenetic markers and injury risk. Our study highlights the
Robert T. Brooke+12 more
wiley +1 more source
Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome [PDF]
Jeannie T. Lee
openalex +1 more source
Epigenomics in cancer management
The identification of all epigenetic modifications implicated in gene expression is the next step for a better understanding of human biology in both normal and pathological states. This field is referred to as epigenomics, and it is defined as epigenetic changes (ie, DNA methylation, histone modifications and regulation by noncoding RNAs such as ...
openaire +6 more sources