Results 131 to 140 of about 55,460 (328)
Quantitative DNA Methylation Analysis: The Promise of High-Throughput Epigenomic Diagnostic Testing in Human Neoplastic Disease [PDF]
, 2006 William B. Coleman, Ashley G. Rivenbark
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Human Molecular Genetics, 2002 Research in cancer epigenomics is driven by the development of novel technologies and the utilization of model organisms ranging from yeasts to plants to vertebrates. For decades, the search for cancer genes has focused on genetic defects that were used as tags for identification of these genes.
openaire +2 more sources
BMEMat, EarlyView.This perspective positions Stereo‐cell as a scalable, unbiased capture platform that unifies phenotypes, spatial context, transcriptomics, proteomics, and EV detection on‐chip. By integrating imaging and CITE‐style readouts with subcellular spatial transcriptomics, it resolves rare and large cells alike. We highlight applications from PBMC benchmarking
Chao Wang +7 more
wiley +1 more source
Lactylation in cancer biology: Unlocking new avenues for research and therapy
Cancer Communications, EarlyView.Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou +6 more
wiley +1 more source
Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain
Developmental Dynamics, EarlyView.Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina +12 more
wiley +1 more source
Cancer: From a Genetic Disorder to a Systemic Disease
Advanced Science, EarlyView.
Ada Hang‐Heng Wong, Yuming Hu
wiley +1 more source
A pilot study on DNA methylation changes for non‐invasive molecular diagnostics in heart failure
ESC Heart Failure, EarlyView.A liquid biopsy approach integrating the high‐resolution RRBS DNA methylation platform and network‐oriented strategy identified the hypomethylation of CPTA1, CKAP4, SPTB, SYT6, EIF2S2, and RAB11FIP1 genes as useful biomarkers in distinguishing between ischaemic and non‐ischaemic HF aetiologies.
Giuditta Benincasa +7 more
wiley +1 more source
Comparative epigenomics of human and mouse mammary tumors [PDF]
, 2008 Berna Demircan +5 more
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Environmental and Molecular Mutagenesis, EarlyView.Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk +4 more
wiley +1 more source