Results 11 to 20 of about 35,782 (293)
Integrating Epigenomics into the Understanding of Biomedical Insight
Bioinformatics and Biology Insights, 2016 Epigenetics is one of the most rapidly expanding fields in biomedical research, and the popularity of the high-throughput next-generation sequencing (NGS) highlights the accelerating speed of epigenomics discovery over the past decade.
Yixing Han, Ximiao He
doaj +2 more sources
Epigenomics and chromatin dynamics [PDF]
Genome Biology, 2012 A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012.
Akopian, Veronika +14 more
openaire +7 more sources
Epigenomics in cancer management
Cancer Management and Research, 2010 Fabricio F CostaCancer Biology and Epigenomics Program, Children’s Memorial Research Center and Northwestern University’s Feinberg School of Medicine, 2430 N.
Fabricio F Costa
doaj +1 more source
Epigenomics in environmental health [PDF]
Frontiers in Genetics, 2011 This review considers the emerging relationships between environmental factors and epigenetic alterations and the application of genome-wide assessments to better define these relationships.
Carmen J Marsit, Brock C Christensen
doaj +3 more sources
Epigenetics and Epigenomics: the future of nutritional interventions? [PDF]
, 2017 Epigenetics and Epigenomics: the future of nutritional ...
Beth Hussey (1248618) +2 more
core +9 more sources
Spatial biology in cancer epigenetics. [PDF]
Mol OncolSpatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Crespo-García E, Esteller M.
europepmc +2 more sources
The SEQC2 epigenomics quality control (EpiQC) study [PDF]
, 2021 Background: Cytosine modifications in DNA such as 5-methylcytosine (5mC) underlie a broad range of developmental processes, maintain cellular lineage specification, and can define or stratify types of cancer and other diseases.
Scherer, Andreas +4 more
core +4 more sources
Genomic Medicine, 2008 'Epigenomics' can be termed as the study of the effects of chromatin structure, including the higher order of chromatin folding and attachment to the nuclear matrix, packaging of DNA around nucleosomes, covalent modifications of histone tails and DNA methylation. This has evolved to include any process that alters gene activity without changing the DNA
Virendra S, Gomase, Somnath, Tagore
+7 more sources
Frontiers in Oncology, 2013 It is well known that Neuroblastoma (NB) patients whose tumors have an undifferentiated histology and a transcriptome enriched in cell cycle genes have a worse prognosis. This contrasts with the good prognoses of patients whose tumors have histologic evidence of differentiation and a transcriptome enriched in differentiation genes.
He, Stanley +3 more
openaire +3 more sources
Neuroblastoma and the epigenome [PDF]
Cancer and Metastasis Reviews, 2021 AbstractNeuroblastoma (NB) is a pediatric cancer of the sympathetic nervous system and one of the most common solid tumors in infancy. Amplification of MYCN, copy number alterations, numerical and segmental chromosomal aberrations, mutations, and rearrangements on a handful of genes, such as ALK, ATRX, TP53, RAS/MAPK pathway genes, and TERT, are ...
Irfete S. Fetahu, Sabine Taschner-Mandl
openaire +2 more sources