Results 11 to 20 of about 33,317 (303)
Integrating Epigenomics into the Understanding of Biomedical Insight
Bioinformatics and Biology Insights, 2016 Epigenetics is one of the most rapidly expanding fields in biomedical research, and the popularity of the high-throughput next-generation sequencing (NGS) highlights the accelerating speed of epigenomics discovery over the past decade.
Yixing Han, Ximiao He
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Circulation Research, 2018 The advent of high-throughput epigenome mapping technologies has ushered in a new era of multiomics where powerful tools can now delineate and record different layers of genomic output. Integrating various components of the epigenome from these multiomics measurements allows the interrogation of cellular heterogeneity in addition to the discovery of ...
Kevin C, Wang, Howard Y, Chang
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Epigenomics and chromatin dynamics [PDF]
Genome Biology, 2012 A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012.
Akopian, Veronika +14 more
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Epigenomics in environmental health [PDF]
Frontiers in Genetics, 2011 This review considers the emerging relationships between environmental factors and epigenetic alterations and the application of genome-wide assessments to better define these relationships.
Carmen J Marsit, Brock C Christensen
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Epigenomics in cancer management
Cancer Management and Research, 2010 Fabricio F CostaCancer Biology and Epigenomics Program, Children’s Memorial Research Center and Northwestern University’s Feinberg School of Medicine, 2430 N.
Fabricio F Costa
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The SEQC2 epigenomics quality control (EpiQC) study [PDF]
, 2021 Background: Cytosine modifications in DNA such as 5-methylcytosine (5mC) underlie a broad range of developmental processes, maintain cellular lineage specification, and can define or stratify types of cancer and other diseases.
Scherer, Andreas +4 more
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Genomic Medicine, 2008 'Epigenomics' can be termed as the study of the effects of chromatin structure, including the higher order of chromatin folding and attachment to the nuclear matrix, packaging of DNA around nucleosomes, covalent modifications of histone tails and DNA methylation. This has evolved to include any process that alters gene activity without changing the DNA
Virendra S, Gomase, Somnath, Tagore
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BMC Gastroenterology, 2021 Background Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis, primarily due to failed early detection. HCC screening is recommended among individuals with cirrhosis using biannual abdominal ultrasound, for earlier ...
Jörn Lewin +13 more
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Titration-based normalization of antibody amount improves consistency of ChIP-seq experiments
BMC Genomics, 2023 Chromatin immunoprecipitation (ChIP) is an antibody-based approach that is frequently utilized in chromatin biology and epigenetics. The challenge in experimental variability by unpredictable nature of usable input amounts from samples and undefined ...
Ariel Caride +11 more
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Neuroblastoma and the epigenome [PDF]
Cancer and Metastasis Reviews, 2021 AbstractNeuroblastoma (NB) is a pediatric cancer of the sympathetic nervous system and one of the most common solid tumors in infancy. Amplification of MYCN, copy number alterations, numerical and segmental chromosomal aberrations, mutations, and rearrangements on a handful of genes, such as ALK, ATRX, TP53, RAS/MAPK pathway genes, and TERT, are ...
Irfete S. Fetahu, Sabine Taschner-Mandl
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