Results 21 to 30 of about 43,487 (351)
Cell, 2012 The eukaryotic genome is packaged into a highly ordered chromatin structure, with specific domains regulating the transcription patterns of local genes. Hathaway et al. now present a breakthrough technique in the artificial induction of chromatin marks and use this experimental model to test the properties of an induced heterochromatic domain.
Oliver J. Rando, Benjamin R. Carone
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Brazilian Archives of Biology and Technology, 2022 DNA methylation and Histone are the main constituents to oversee the stable maintenance of cellular phenotypes. Any abnormalities in these components could cause cancer development and, therefore, must be potentially diagnostic.
Wakar Ahmad +3 more
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Social Epigenomics: Conceptualizations and Considerations for Oral Health
Journal of dentistry research, 2022 Advances in high-throughput technologies and the generation of multiomics, such as genomic, epigenomic, transcriptomic, and metabolomic data, are paving the way for the biological risk stratification and prediction of oral diseases.
N. Gomaa
semanticscholar +1 more source
Cell Death and Disease, 2023 Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer development. COPD induces activation of hypoxia-induced signaling, causing remodeling of surrounding microenvironmental cells also modulating the release and cargo of their ...
Ilaria Petraroia +10 more
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BMC Research Notes, 2019 Objective DNA methylation analysis via real-time PCR or other analytical techniques requires purified bisulfite converted DNA. We report on an automated high throughput solution for DNA extraction, bisulfite-conversion, and purification of 96 samples ...
Sebastian Rausch +4 more
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RNA N6-methyladenosine methylation and skin diseases
Autoimmunity, 2023 Skin diseases are global health issues caused by multiple pathogenic factors, in which epigenetics plays an invaluable role. Post-transcriptional RNA modifications are important epigenetic mechanism that regulate gene expression at the genome-wide level.
Yaqin Yu +6 more
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Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci
Circulation Research, 2021 Supplemental Digital Content is available in the text. Rationale: Genome-wide association studies have identified hundreds of loci associated with coronary artery disease (CAD).
T. Örd +12 more
semanticscholar +1 more source
Social epigenomics: are we at an impasse?
Epigenomics, 2021 Aim: Social scientists have placed particularly high expectations on the study of epigenomics to explain how exposure to adverse social factors like poverty, child maltreatment and racism - particularly early in childhood - might contribute to complex ...
A. Non
semanticscholar +1 more source
Enhanced JBrowse plugins for epigenomics data visualization
BMC Bioinformatics, 2018 Background New sequencing techniques require new visualization strategies, as is the case for epigenomics data such as DNA base modifications, small non-coding RNAs, and histone modifications.
Brigitte T. Hofmeister +1 more
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Epigenomics, 2021 Epigenomics is the collective study of all epigenetic modifications that can affect the genome, the most pivotal of which are DNA methylation (DNAm), histone modifications (e.g., acetylation, citrullination and phosphorylation) and nucleosome remodeling.
Milad Shirvaliloo
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