Results 31 to 40 of about 57,741 (321)
Nature Communications, 2022 While cutaneous melanoma is linked to UV radiation, acral melanoma is not. Epigenetic mechanisms function as sensors to exposures and determinants of cell identity.
Anna Luiza Silva Almeida Vicente +12 more
doaj +1 more source
Probing the cancer genome [PDF]
, 2011 A report on the Keystone Symposium 'Cancer Genomics and Epigenomics', Taos, USA, 19-24 February ...
Greulich, Heidi E.
core +1 more source
Epigenomics and Chromatin Dynamics [PDF]
, 2014 A report of the 'Joint Keystone Symposium on Epigenomics and Chromatin Dynamics', Keystone, Colorado, 17-22 January 2012. This year's Joint Keystone Symposium on Epigenomics and Chromatin Dynamics was one of the largest Keystone meetings to date ...
Akopian, Veronika +14 more
core +1 more source
What is a Gene? A Two Sided View [PDF]
, 2017 The need to account for all currently available experimental observations concerning the gene nature, has reshaped the concept of gene turning it from the essentially mechanistic unit, predominant during the '70s, into a quite abstract open ...
Bolondi, A. +8 more
core +1 more source
Chromatin insulator elements: establishing barriers to set heterochromatin boundaries [PDF]
, 2012 Epigenomic profiling has revealed that substantial portions of genomes in higher eukaryotes are organized into extensive domains of transcriptionally repressive chromatin.
Adam G West +9 more
core +1 more source
Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage. [PDF]
, 2020 During puberty, a woman's breasts are vulnerable to environmental damage ("window of vulnerability"). Early exposure to environmental carcinogens, endocrine disruptors, and unhealthy foods (refined sugar, processed fats, food additives) are hypothesized ...
Aljaber, Dana +19 more
core +1 more source
Nature Communications, 2021 Muco-obstructive lung diseases are characterised by airway macrophage (AM) populations which may have epigenetic changes. Here using a mouse model the authors show epigenetic alteration of AMs with changes in LPS response, phagocytosis and efferocytosis ...
Joschka Hey +9 more
doaj +1 more source
Scientific Reports, 2023 Ectopic fat deposition is more strongly associated with obesity-related health problems including type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), hypothyroidism, arthritis, etc.
Sunandini Ghosh +4 more
doaj +1 more source
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. [PDF]
, 2010 Analysis of DNA methylation patterns relies increasingly on sequencing-based profiling methods. The four most frequently used sequencing-based technologies are the bisulfite-based methods MethylC-seq and reduced representation bisulfite sequencing (RRBS),
A Bird +79 more
core +2 more sources
Nature Communications, 2018 Th17 cells are a common pathogenic effector cell in autoimmune inflammatory diseases. Here the authors show that the transcription factor RFX1 limits Th17 differentiation and is protective against the pathogenesis of Th17-driven autoimmune diseases.
Ming Zhao +15 more
doaj +1 more source