Results 61 to 70 of about 64,265 (410)
Epigenomics, 2021 This article describes ethnography as a research method and outlines how it excels in capturing the salient experiences of individuals among diverse communities in their own words.
M. Lock +2 more
semanticscholar +1 more source
Epigenomes in Cardiovascular Disease. [PDF]
, 2018 If unifying principles could be revealed for how the same genome encodes different eukaryotic cells and for how genetic variability and environmental input are integrated to impact cardiovascular health, grand challenges in basic cell biology and ...
McKinsey TA +4 more
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The allure of the epigenome [PDF]
Genome Biology, 2012 The Oxford English Dictionary dates the word 'genome' to 1926 but has not yet seen fit to include the term 'epigenome' in its illustrious pages (where it would reside handsomely between 'epigenist' and 'epigenous'). This differential treatment reflects a state of affairs in which the epigenome has yet to infiltrate the popular imagination, but belies ...
openaire +3 more sources
Nature Reviews Immunology, 2021 A new study in Cell provides a single-cell map of the epigenetic and transcriptomic landscape in response to influenza vaccination, revealing persistent epigenomic remodelling in myeloid cells and the antiviral effects of adjuvant.
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Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
Kernel-Based Testing for Single-Cell Differential Analysis [PDF]
arXiv, 2023 Single-cell technologies offer insights into molecular feature distributions, but comparing them poses challenges. We propose a kernel-testing framework for non-linear cell-wise distribution comparison, analyzing gene expression and epigenomic modifications.
arxiv
Educating Future Nursing Scientists: Recommendations for Integrating Omics Content in PhD Programs [PDF]
, 2015 Preparing the next generation of nursing scientists to conduct high-impact, competitive, sustainable, innovative, and interdisciplinary programs of research requires that the curricula for PhD programs keep pace with emerging areas of knowledge and ...
Cindy M. Anderson +13 more
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eLife, 2022 A new approach helps to assess the impact of accelerated epigenetic aging on the risk of cancer.
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Molecular Cell, 2016 During aging, the mechanisms that normally maintain health and stress resistance strikingly decline, resulting in decrepitude, frailty, and ultimately death. Exactly when and how this decline occurs is unknown. Changes in transcriptional networks and chromatin state lie at the heart of age-dependent decline.
Lauren N. Booth, Anne Brunet
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Nature Communications, 2021 Muco-obstructive lung diseases are characterised by airway macrophage (AM) populations which may have epigenetic changes. Here using a mouse model the authors show epigenetic alteration of AMs with changes in LPS response, phagocytosis and efferocytosis ...
Joschka Hey +9 more
doaj +1 more source