Results 11 to 20 of about 212,176 (344)
Iron Inhibits the Translation and Activity of the Renal Epithelial Sodium Channel [PDF]
Biology, 2022 Hypertension is associated with an increased renal expression and activity of the epithelial sodium channel (ENaC) and iron deficiency. Distal tubules absorb iron, causing perturbations that may influence local responses.
Abdel A. Alli +8 more
doaj +2 more sources
Epithelial Sodium Channel Inhibition by Amiloride Addressed with THz Spectroscopy and Molecular Modeling [PDF]
Molecules, 2022 THz spectroscopy is important for the study of ion channels because it directly addresses the low frequency collective motions relevant for their function. Here we used THz spectroscopy to investigate the inhibition of the epithelial sodium channel (ENaC)
Maria Mernea +7 more
doaj +2 more sources
The role of the epithelial Na+ channel (ENaC) in high AVP but low aldosterone states [PDF]
Frontiers in Physiology, 2012 Due to the abundance of seminal discoveries establishing a strong causal relation between changes in aldosterone signaling, the activity of the epithelial Na+ channel (ENaC) and blood pressure, the role of ENaC in health and disease is understood almost ...
James D Stockand
doaj +3 more sources
Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC [PDF]
Molecular Brain, 2019 This study describes the functional interaction between Cav3.2 calcium channels and the Epithelial Sodium Channel (ENaC). β-ENaC subunits showed overlapping expression with endogenous Cav3.2 calcium channels in the thalamus and hypothalamus as detected ...
Agustin Garcia-Caballero +7 more
doaj +4 more sources
Epithelial Sodium and Chloride Channels and Asthma
Chinese Medical Journal, 2015 Objective: To focus on the asthmatic pathogenesis and clinical manifestations related to epithelial sodium channel (ENaC)/chlorine ion channel. Data Sources: The data analyzed in this review were the English articles from 1980 to 2015 from journal ...
Wen Wang, Hong-Long Ji
doaj +3 more sources
Frontiers in Physiology, 2021 The activity of the Epithelial Na+ Channel (ENaC) in renal principal cells (PC) fine-tunes sodium excretion and consequently, affects blood pressure.
Antonio G. Soares +7 more
doaj +1 more source
Acta Physiologica, 2021 The serine protease prostasin (Prss8) is expressed in the distal tubule and stimulates proteolytic activation of the epithelial sodium channel (ENaC) in co‐expression experiments in vitro.
Daniel Essigke +11 more
semanticscholar +1 more source
Epithelial Sodium Channel [PDF]
Hypertension, 2008 Despite large changes in water and salt intake, the kidney is able to maintain the extracellular osmolarity and volume within narrow margins.1 Such fine control requires specific factors or hormones; among them, aldosterone and vasopressin play key roles.
Bernard C, Rossier, Laurent, Schild
openaire +2 more sources
Reduced expression of Enac in Placenta tissues of patients with severe preeclampsia is related to compromised trophoblastic cell migration and invasion during pregnancy. [PDF]
PLoS ONE, 2013 The purpose of the study is to investigate the expression of epithelial sodium channel (ENaC) in normal pregnancy and severe preeclampsia placenta and to explore the underlying mechanism of the relationship between the altered ENaC expression and onset ...
Shan Wang +7 more
doaj +1 more source
Journal of the American Society of Nephrology, 2020 BACKGROUND Aldosterone activates the intercalated cell mineralocorticoid receptor, which is enhanced with hypokalemia. Whether this receptor directly regulates the intercalated cell chloride/bicarbonate exchanger pendrin is unclear, as are potassium's ...
T. Pham +9 more
semanticscholar +1 more source