Results 111 to 120 of about 607,096 (382)

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

open access: yesNature Communications, 2019
The magnitude of T cell responses to infection is a function of the naïve T cell repertoire combined with the context and duration of antigen presentation. Using mass spectrometry, we identify and quantify 21 class 1 MHC-restricted influenza A virus (IAV)
Ting Wu   +11 more
semanticscholar   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser   +5 more
wiley   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li   +9 more
wiley   +1 more source

237 Epitope engineered hematopoietic stem cells to enable multi-specificity CAR-T cells for acute myeloid leukemia [PDF]

open access: hybrid, 2023
Gabriele Casirati   +14 more
openalex   +1 more source

An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction

open access: yesJournal of Immunological Research, 2016
Identification of B‐cell epitopes is a fundamental step for development of epitope‐based vaccines, therapeutic antibodies, and diagnostic tools. Epitope‐based antibodies are currently the most promising class of biopharmaceuticals. In the last decade, in‐
L. Potocnakova, M. Bhide, L. Pulzova
semanticscholar   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

An Epitope‐Imprinted Biointerface with Dynamic Bioactivity for Modulating Cell–Biomaterial Interactions

open access: yesAngewandte Chemie, 2017
In this study, an epitope‐imprinting strategy was employed for the dynamic display of bioactive ligands on a material interface. An imprinted surface was initially designed to exhibit specific affinity towards a short peptide (i.e., the epitope).
G. Pan   +6 more
semanticscholar   +1 more source

The short-lived MATα2 transcriptional regulator is ubiquitinated in vivo [PDF]

open access: yes, 1991
The substrates of ubiquitin-dependent proteolytic pathways include both damaged or otherwise abnormal proteins and undamaged proteins that are naturally short-lived. Few specific examples of the latter class have been identified, however.
Chau, Vincent   +3 more
core  

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

Humoral Epitope Spreading in Autoimmune Bullous Diseases

open access: yesFrontiers in Immunology, 2018
Autoimmune blistering diseases are characterized by autoantibodies against structural adhesion proteins of the skin and mucous membranes. Extensive characterization of their autoantibody targets has improved understanding of pathogenesis and laid the ...
D. Didona, G. Di Zenzo
semanticscholar   +1 more source

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