Results 111 to 120 of about 554,474 (398)
Epitopes in ChEBI - A Collaboration with the IEDB [PDF]
, 2010 *ChEBI background:* Chemical Entities of Biological Interest (ChEBI) is a curated database of small chemical entities important in biosystems. As well as a description of entities, it provides a semantically rich knowledge base; and an internal hierarchy
Bjoern Peters +7 more
core +2 more sources
Non-Toxin-Based Clostridioides difficile Vaccination Approaches
Pathogens, 2023 Clostridioides difficile (CD) is a Gram-positive, anaerobic bacterium that infects mainly hospitalized and elderly people who have been treated with long-term antibiotic therapy leading to dysbiosis.
Agnieszka Razim +2 more
doaj +1 more source
Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis [PDF]
, 2009 Antibodies to citrulline-modifi ed proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear.
Aho +69 more
core +2 more sources
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Advances in the Characterization of the T-Cell Response to Human Herpesvirus-6
Frontiers in Immunology, 2018 Human herpesvirus (HHV) 6 is thought to remain clinically latent in most individuals after primary infection and to reactivate to cause disease in persons with severe immunosuppression.
Derek J. Hanson +8 more
doaj +1 more source
PeBLes: Prediction of B-cell epitope using molecular layers [PDF]
arXiv, 2016 Characterization of B-cell protein epitope and developing critical parameters for its identification is one of the long standing interests. Using Layers algorithm, we introduced the concept of anchor residues to identify epitope. We have shown that majority of the epitope is composed of anchor residues and have significant bias in epitope for these ...
arxiv
Application of built-in adjuvants for epitope-based vaccines
PeerJ, 2019 Several studies have shown that epitope vaccines exhibit substantial advantages over conventional vaccines. However, epitope vaccines are associated with limited immunity, which can be overcome by conjugating antigenic epitopes with built-in adjuvants (e.
Y. Lei +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source
GII.4 Human Norovirus: Surveying the Antigenic Landscape
Viruses, 2019 Human norovirus is the leading cause of viral acute onset gastroenteritis disease burden, with 685 million infections reported annually. Vulnerable populations, such as children under the age of 5 years, the immunocompromised, and the elderly show a need
Michael L. Mallory +3 more
doaj +1 more source
Gene doctoring: a method for recombineering in laboratory and pathogenic Escherichia coli strains [PDF]
, 2009 Background: Homologous recombination mediated by the lambda-Red genes is a common method for making chromosomal modifications in Escherichia coli.
Bingle, Lewis EH +6 more
core +4 more sources