Results 241 to 250 of about 12,449,745 (282)

The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes

The Journal of Immunology, 1993
Abstract CD22 is a B lineage-restricted member of the Ig superfamily that serves as an adhesion receptor expressed by mature B lymphocytes. In this study, the ability of different cell types to attach to COS cells transiently transfected with a full-length CD22 cDNA (COS-CD22) was examined to determine the cellular distribution of the
P, Engel   +6 more
openaire   +2 more sources

Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes

Immunological Reviews, 1998
Summary: A complex interplay of cells, soluble macromolecules, and antigen lead to a productive immune response that evolved for the survival of species. While the immune system is intended to protect from foreign agents, such as bacterial and viral infection, the presence of autoimmune diseases indicates that the system is not perfect in ...
Mark J. Mamula, Mark J. Mamula
openaire   +2 more sources

Expression and purification of a soluble B lymphocyte stimulator mutant modified with the T-helper cell epitope

Biotechnology Letters, 2006
The DNA encoding soluble B lymphocyte stimulator (134-285 amino acids, sBLyS) mutant with residues 217-224 replaced by two glycines (named msBLyS) was constructed. The sequence encoding a foreign immunodominant T-helper epitope from ovalbumin (OVA) was then coupled to the 5'-end of msBLyS cDNA.
Huiguang, Gao   +7 more
openaire   +2 more sources

Analysis of the repertoire of human B‐lymphocytes specific for type A and type B blood group terminal trisaccharide epitopes

Transfusion, 1993
Naturally occurring serum antibodies specific for the A and B blood group isoantigens are of great importance in medicine. By using A‐type terminal trisaccharide (ATS) or B‐type terminal trisaccharide (BTS) coupled to albumin as coating antigens, an enzyme‐linked immunosorbent assay capable of detecting all ATS/BTS‐binding antibodies was performed. The
J D, Conger, M M, Chan, L, DePalma
openaire   +2 more sources

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