Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]
, 2005 Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Bertoletti, A. +9 more
core +1 more source
Immunomodulation by imiquimod in patients with high-risk primary melanoma. [PDF]
, 2012 Imiquimod is a synthetic Toll-like receptor 7 (TLR7) agonist approved for the topical treatment of actinic keratoses, superficial basal cell carcinoma, and genital warts.
Antoni Ribas +48 more
core +2 more sources
Identification of Theileria lestoquardi Antigens Recognized by CD8+ T Cells. [PDF]
PLoS ONE, 2016 As part of an international effort to develop vaccines for Theileria lestoquardi, we undertook a limited screen to test T. lestoquardi orthologues of antigens recognised by CD8+ T lymphocyte responses against T. annulata and T. parva in cattle.
Shan Goh +10 more
doaj +1 more source
Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]
, 2013 Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E. +4 more
core +2 more sources
Frontiers in Immunology, 2017 The threat posed by severe congenital abnormalities related to Zika virus (ZKV) infection during pregnancy has turned development of a ZKV vaccine into an emergency.
Edecio Cunha-Neto +11 more
doaj +1 more source
Journal of Experimental Medicine, 1997 Association of antigenic peptides with newly synthesized major histocompatibility complex (MHC) class I molecules occurs in the endoplasmic reticulum and is a critical early step for the initiation of cytotoxic T lymphocyte (CTL)-mediated immune defenses.
A. Sijts, E. Pamer
semanticscholar +1 more source
Identification of cytotoxic T‐lymphocyte epitope(s) and its agonist epitope(s) of a novel target for vaccine therapy (PAGE4) [PDF]
International Journal of Cancer, 2007 AbstractPAGE4 is an X chromosome‐linked cancer testis antigen and is a potential new tumor‐associated antigen that is overexpressed in prostate and uterine cancers. The purpose of this study was to identify a human CTL epitope and a corresponding agonist epitope of PAGE4 to determine if PAGE4 is a potential target for vaccine‐mediated immunotherapy ...
Junko Yokokawa +9 more
openaire +3 more sources
Heat shock proteins may be a missing link between febrile infection and cancer tumor rejection via autoantigen molecular mimicry [PDF]
arXiv, 2023 Numerous epidemiological studies suggest febrile infections could confer long-term immunity to certain types of cancers, though the precise mechanisms for this phenomenon remain unclear. Systemic heat-shock responses to fever may be key to understanding the overlapping outcomes of immune responses to infection and cancer. To investigate this hypothesis,
arxiv
An investigation of the breadth of neutralising antibody response in cats naturally infected with feline immunodeficiency virus [PDF]
, 2015 Neutralising antibodies (NAbs) are believed to comprise an essential component of the protective immune response induced by vaccines against FIV and HIV infections.
Beczkowski, Pawel +5 more
core +2 more sources
Recognition of distinct epitopes on the HLA-A2 antigen by cytotoxic T lymphocytes
Human Immunology, 1986 Alloimmune CTLs specifically recognizing the HLA-A2.3 subtype could be made besides the previously described HLA-A2.1 and A2.2 subtype-specific CTLs. Examination of the fine specificity of 15 different CTLs directed against distinct HLA-A2 subtypes demonstrated further complexity of antigenic epitopes present on the A2 molecule.
Goulmy, E.A.J.M. +4 more
openaire +4 more sources