Results 71 to 80 of about 22,519 (238)
Zhongshan Daxue xuebao. Yixue kexue ban, 2020 【目的】研究甲状腺乳头状癌（PTC）中雌激素受体β基因（ERβ）表达及 5′非翻译区甲基化状态，探讨ERβ在 PTC 中低表达的原因。【方法】应用 Western blot 和免疫组织化学染色法检测正常甲状腺细胞Nthy-ori3-1、PTC 细胞 BCPAP 以及正常甲状腺组织、甲状腺结节性增生组织和 PTC 组织ERβ蛋白表达；应用 qRT-PCR 检测各细胞和组织中 ERβ mRNA（0K-1）、ERβ mRNA（0N-1）和总 ERβ mRNA 表达水平；亚硫酸氢盐测序分析各细胞和组织中 ERβ
苟茜, 许琳婉, 刘智敏
doaj
Cell Death and Disease, 2023 Estrogen plays a protective role in colorectal cancer (CRC) and primarily functions through estrogen receptor β (ERβ). However, clinical strategies for CRC therapy associated with ERβ are still under investigation.
Tianqi Liu +12 more
doaj +1 more source
Distances between E2 and ERα and ERβ.
, 2013 Distances between E2 and ERα and ERβ.
Charlie Chandsawangbhuwana (31494) +1 more
core +1 more source
Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice
Journal of Applied Toxicology, EarlyView.ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik +3 more
wiley +1 more source
ERβ target genes identified by ChIP-seq and GRO-seq.
, 2013 A – Gene Ontology analysis shows that ERβ target genes are enriched in anti-proliferative processes such as differentiation and apoptosis. B – Metagene anslysis supports genes differentially regulated by ERβ upon E2 treatment. C, D – C4–12/Flag.ERβ cells
W. Lee Kraus (218839) +4 more
core +1 more source
The Positive and Adverse Childhood Experiences (PACE) Framework for Counseling Youths
Journal of Counseling &Development, EarlyView.ABSTRACT Youth mental and behavioral health are significantly shaped by both adverse childhood experiences (ACEs) and positive childhood experiences (PCEs). Yet, counseling scholarship and training often address these domains separately, limiting their translation to counseling practice.
Isak Kim, Jaeyoung Kim, Gahyun Park
wiley +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Gadolinium‐based contrast agents are used in brain MRI to improve the visualization of disorders and improve the delineation of lesions. Higher doses of GBCAs can improve lesion sensitivity but may have safety implications, particularly in light of recent findings on gadolinium retention and deposition.
Srivathsa Pasumarthi Venkata +10 more
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto +6 more
wiley +1 more source
Overview of ERβ binding regions in C4–12/Flag.ERβ cells.
, 2013 ERβ binding sites identified in C4–12/Flag.ERβ cells (blue) were compared with ERα binding sites in MCF-7 cells (green and red). 524 sites are shared with the ERα landscape reported by Welboren 2009 [15]; 127 sites are shared with ERα landscape reported ...
W. Lee Kraus (218839) +4 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established treatment for Parkinson's disease (PD). Using 7‐Tesla (7 T) MRI connectivity analysis to visualize the patient‐specific STN motor subdivision, we hypothesize that reprogramming patients who are stimulated outside of this subdivision can improve their ...
Yarit Wiggerts +6 more
wiley +1 more source