Results 51 to 60 of about 29,801 (212)

Estrogen receptor β exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib. [PDF]

PLoS ONE, 2010
BACKGROUND: The role of estrogen and estrogen receptors in oncogenesis has been investigated in various malignancies. Recently our group identified estrogen receptor beta (ERβ) expression as an independent prognostic factor in the progression of human ...
Giulia Pinton, Warren Thomas, Paolo Bellini, Arcangela Gabriella Manente, Roberto E Favoni, Brian J Harvey, Luciano Mutti, Laura Moro   +7 more
doaj   +1 more source

On the area of the symmetry orbits in $T^2$ symmetric spacetimes with Vlasov matter

, 2003
This paper treats the global existence question for a collection of general relativistic collisionless particles, all having the same mass. The spacetimes considered are globally hyperbolic, with Cauchy surface a 3-torus.
Andréasson H, Andréasson H, Chru?ciel P, Ehlers J, Isenberg J, Marsha Weaver, Moncrief V, Narita M, Rendall A D, Rendall A D, Weaver M   +10 more
core   +1 more source

The Serine/Threonine Protein Kinase (Akt)/ Protein Kinase B (PkB) Signaling Pathway in Breast Cancer [PDF]

, 2020
According to statistical data published in 2019, breast cancer is among the leading causes of death in women worldwide. The serine/threonine kinase (AKT) or protein kinase B (PkB) signaling pathway is activated by phosphorylation processes, which further
Bratu, Ovidiu Gabriel, Diaconu, Camelia Cristina, Greabu, Maria, Miricescu, Daniela, Rusu, Ioana Ruxandra, Spinu, Dan, Stanescu, Ana Maria Alexandra, Stefani, Constantin, Totan, Alexandra   +8 more
core   +3 more sources

A novel nerve block and anatomy workshop for emergency medicine residents: A pilot study

Anatomical Sciences Education, EarlyView.
Abstract Construct a workshop for emergency medicine (EM) residents to learn ultrasound‐guided regional anesthesia (UGRA) procedures and build confidence in performing those procedures. Use pre‐ and post‐workshop knowledge and confidence surveys to determine workshop effectiveness.
Geoffery D. Fernquist, Derek Harmon, Lauren D. Branditz, Andrew Kendle, Melissa M. Quinn   +4 more
wiley   +1 more source

Estrogen receptor β exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity.

PLoS ONE, 2020
Estrogen receptor β (ERβ) was first identified in the rodent prostate and is abundantly expressed in human and rodent prostate epithelium, stroma, immune cells and endothelium of the blood vessels.
Surendra Chaurasiya, Scott Widmann, Cindy Botero, Chin-Yo Lin, Jan-Åke Gustafsson, Anders M Strom   +5 more
doaj   +1 more source

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells [PDF]

, 2017
open12noBreast cancer (BC) is one of the major causes of cancer death in women and is closely related to hormonal dysregulation. Estrogen receptor (ER)-positive BCs are generally treated with anti hormone therapy using antiestrogens or aromatase ...
CARRA, Serena, Cicardi, Maria Elena, Crippa, Valeria, Cristofani, Riccardo, Ferri, Nicola, Galbiati, Mariarita, Meroni, Marco, Messi, Elio, MORELLI, FEDERICA FRANCESCA, Piccolella, Margherita, Poletti, Angelo, Rusmini, Paola   +11 more
core   +3 more sources

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

The role of estrogen receptor beta in breast cancer

Biomarker Research, 2020
Breast cancer, a malignant tumor originating from mammary epithelial tissue, is the most common cancer among women worldwide. Challenges facing the diagnosis and treatment of breast cancer necessitate the search for new mechanisms and drugs to improve ...
Yujing Zhou, Xingdang Liu
doaj   +1 more source

The Prognostic Value of Estrogen Receptor β Isoform With Correlation of Estrogen Receptor α Among Sudanese Breast Cancer Patients

Breast Cancer: Basic and Clinical Research, 2021
Two estrogen receptor isoforms (ERα and ERβ) have been characterized with variable and sometimes contrasting responses to estrogens, partially explained by different receptor signaling pathways in estrogen-sensitive tissues.
Manar G Shalabi, Anass M Abbas, Jeremy Mills, Mohamed A Kheirelseid, Abozer Y Elderdery   +4 more
doaj   +1 more source

Molecular analysis of endocrine disruption in hornyhead turbot at wastewater outfalls in southern california using a second generation multi-species microarray. [PDF]

, 2013
Sentinel fish hornyhead turbot (Pleuronichthysverticalis) captured near wastewater outfalls are used for monitoring exposure to industrial and agricultural chemicals of ~ 20 million people living in coastal Southern California.
Angert, Mila, Baker, Michael E, Bay, Steven M, Carnevali, Oliana, Gully, Joseph R, Hardiman, Gary, Kelley, Kevin M, Lekmine, Narimene, Ludka, Colleen, Martella, Andrea, Ribecco, Cataldo, Ricciardelli, Eugenia, Schlenk, Daniel, Sprague, L James, Vidal-Dorsch, Doris E, Šášik, Roman   +15 more
core   +2 more sources