Results 31 to 40 of about 22,519 (238)

Prostate Tumorigenesis Induced by PTEN Deletion Involves Estrogen Receptor β Repression

Cell Reports, 2015
The role of ERβ in prostate cancer is unclear, although loss of ERβ is associated with aggressive disease. Given that mice deficient in ERβ do not develop prostate cancer, we hypothesized that ERβ loss occurs as a consequence of tumorigenesis caused by ...
Paul Mak, Jiarong Li, Sanjoy Samanta, Cheng Chang, D. Joseph Jerry, Roger J. Davis, Irwin Leav, Arthur M. Mercurio   +7 more
doaj   +1 more source

Betulinic Acid Inhibits Endometriosis Through Suppression of Estrogen Receptor β Signaling Pathway

Frontiers in Endocrinology, 2020
Endometriosis is an inflammatory gynecological disorder characterized by endometrial tissue growth located outside of the uterine cavity in addition to chronic pelvic pain and infertility.
Dongfang Xiang, Min Zhao, Xiaofan Cai, Yongxia Wang, Lei Zhang, Helen Yao, Min Liu, Huan Yang, Mingtao Xu, Huilin Li, Huijuan Peng, Min Wang, Xuefang Liang, Ling Li, Paul Yao, Paul Yao   +15 more
doaj   +1 more source

Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer

npj Breast Cancer, 2022
Triple Negative Breast Cancer (TNBC) accounts for 15–20% of all breast cancer cases, yet is responsible for a disproportionately high percentage of breast cancer mortalities.
Kirsten G. M. Aspros, Jodi M. Carter, Tanya L. Hoskin, Vera J. Suman, Malayannan Subramaniam, Michael J. Emch, Zhenqing Ye, Zhifu Sun, Jason P. Sinnwell, Kevin J. Thompson, Xiaojia Tang, Esther P. B. Rodman, Xiyin Wang, Adam W. Nelson, Igor Chernukhin, Feda H. Hamdan, Elizabeth S. Bruinsma, Jason S. Carroll, Martin E. Fernandez-Zapico, Steven A. Johnsen, Krishna R. Kalari, Haojie Huang, Roberto A. Leon-Ferre, Fergus J. Couch, James N. Ingle, Matthew P. Goetz, John R. Hawse   +26 more
doaj   +1 more source

Phytoestrogenic Activity of Blackcurrant Anthocyanins Is Partially Mediated through Estrogen Receptor Beta

Molecules, 2017
Phytoestrogens are plant compounds with estrogenic effects found in many foods. We have previously reported phytoestrogen activity of blackcurrant anthocyanins (cyanidin-3-glucoside, cyanidin-3-rutinoside, delphinidin-3-glucoside, and delphinidin-3 ...
Naoki Nanashima, Kayo Horie, Hayato Maeda   +2 more
doaj   +1 more source

Urethral dysfunction in female mice with estrogen receptor β deficiency. [PDF]

PLoS ONE, 2014
Estrogen has various regulatory functions in the growth, development, and differentiation of the female urogenital system. This study investigated the roles of ERβ in stress urinary incontinence (SUI).
Yung-Hsiang Chen, Chao-Jung Chen, Shuyuan Yeh, Yu-Ning Lin, Yang-Chang Wu, Wen-Tsong Hsieh, Bor-Tsang Wu, Wen-Lung Ma, Wen-Chi Chen, Chawnshang Chang, Huey-Yi Chen   +10 more
doaj   +1 more source

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer. [PDF]

, 2014
Downmodulation or loss-of-function mutations of the gene encoding NOTCH1 are associated with dysfunctional squamous cell differentiation and development of squamous cell carcinoma (SCC) in skin and internal organs.
Cerveny, K., Hofbauer, G.F., Chiorino, G., Dotto, G.P., Jo, S.H., Lefort, K., Dziunycz, P., Ostano, P., Brooks, Y.S., Dai, J., Getsios, S.   +10 more
core   +2 more sources

Genotyping of different ERβ mutant mice.

, 2014
Lane 1, ERβ+/+ mice; Lane 2, ERβ+/- mice; Lane 3, ERβ-/- mice.
Chao-Jung Chen (499918), Bor-Tsang Wu (638530), Huey-Yi Chen (638532), Wen-Lung Ma (638531), Chawnshang Chang (214921), Shuyuan Yeh (214920), Yu-Ning Lin (638528), Yang-Chang Wu (4607), Yung-Hsiang Chen (135206), Wen-Chi Chen (286343), Wen-Tsong Hsieh (638529)   +10 more
core   +1 more source

ERβ associates with EGFR and caveolin 1.

, 2013
A) Co-immunoprecipitation experiments were performed on REN cells treated 1 and 5 minutes with 5 ng/ml of human recombinant EGF. ERβ and caveolin 1 were detected by Western blot in immunoprecipitations of membrane associated EGFR.
Roberto E. Favoni (359446), Arcangela Gabriella Manente (165477), Giulia Pinton (165469), Paolo Bellini (359445), Laura Moro (165495), Luciano Mutti (165489), Warren Thomas (359444), Brian J. Harvey (321613)   +7 more
core   +1 more source

ANALISIS IN SILICO GENISTEIN DAN ANALOGNYA SEBAGAI INHIBITOR KANKER PAYUDARA RESEPTOR ESTROGEN ALFA POSITIF (ERα+)

JURNAL FARMASI GALENIKA, 2017
Breast cancer is the highest mortality disease on women in the world and about 60-80% of the cases are ERα+ breast cancer. The discovery of more selective to HERα, safe, and potential new anticancer agent is expected to help the treatment of ERα+ breast cancer.
openaire   +1 more source

Distances between MBP and ERβ.

, 2013
Distances between MBP and ERβ.
Charlie Chandsawangbhuwana (31494), Michael E. Baker (27422)   +1 more
core   +1 more source