Estrogen receptor β agonist inhibits proliferation of endometrial stromal cells in an estrogen-receptor independent manner [PDF]
The finding that estrogen receptor ERβ agonists induce regression of ectopic endometrial implants in a rodent model has rekindled interest in the role of ERβ in the growth and maintenance of human endometriosis.
Xia Qiong, Zhao Dong, Wang Juan
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Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
Background Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and ovulation, yet its exact mechanism of action is mainly uncharacterized.
Madeleine Birgersson +7 more
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Gene expression of estrogen receptor during different stages of pregnancy in rats model [PDF]
One essential organ that steroid hormones target is the uterus and ovaries. Many receptors mediate the effects of these hormones such as estrogen receptors ER.
Enas O. Al-Babily, Barra D. Al-Watar
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Estrogen Receptor β Agonists Differentially Affect the Growth of Human Melanoma Cell Lines. [PDF]
Cutaneous melanoma is an aggressive malignancy; its incidence is increasing worldwide and its prognosis remains poor. Clinical observations indicate that estrogen receptor β (ERβ) is expressed in melanoma tissues and its expression decreases with tumor ...
Monica Marzagalli +4 more
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Background Estrogen receptor β (ERβ) is the major ER subtype in hepatic stellate cells (HSCs). Previously we reported phytoestrogen calycosin suppressed liver fibrosis progression and inhibited HSC-T6 cell functions, suggesting the effects may be related
Yaxin Wang +4 more
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A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function
The two homologous estrogen receptors ERα and ERβ exert distinct effects on their cognate tissues. Previous work from our laboratory identified an ERβ-specific phosphotyrosine residue that regulates ERβ transcriptional activity and antitumor function in ...
Bin Yuan +4 more
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Expression of extracellular matrix components is disrupted in the immature and adult estrogen receptor β-null mouse ovary. [PDF]
Within the ovary, Estrogen Receptor β (ERβ) is localized to the granulosa cells of growing follicles. 17β-estradiol (E2) acting via ERβ augments the actions of follicle stimulating hormone in granulosa cells, leading to granulosa cell differentiation and
Alexandra Zalewski +2 more
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Estrogen receptor beta (ERß) In gastric cancer – A systematic review and meta-analysis [PDF]
Introduction: Gastric cancer represents a major public health challenge worldwide due to its significant morbidity and mortality rates. Among the factors associated with the development of gastric cancer, estrogen receptor beta (ERβ) has emerged as a ...
S. Peri, Y. Niv
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Estrogen, through its receptors, regulates various aspects of spermatogenesis and male fertility. To understand the roles of estrogen receptors (ERα and ERβ) in male fertility, we have developed in vivo selective ER agonist administration models ...
Kushaan Dumasia +3 more
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TRIM16 transcription factor in prostate cancer
The aim of this investigation was to reveal the expression TRIM16, ERα, ERβ and AR in prostate cancer tissues compared to benign hyperplasia and clinical and morphological parameters.Materials and methods.
L. V. Spirina +5 more
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