Results 21 to 30 of about 29,801 (212)
Estrogen receptor beta (ERß) In gastric cancer – A systematic review and meta-analysis [PDF]
Introduction: Gastric cancer represents a major public health challenge worldwide due to its significant morbidity and mortality rates. Among the factors associated with the development of gastric cancer, estrogen receptor beta (ERβ) has emerged as a ...
S. Peri, Y. Niv
doaj +1 more source
Expression of extracellular matrix components is disrupted in the immature and adult estrogen receptor β-null mouse ovary. [PDF]
Within the ovary, Estrogen Receptor β (ERβ) is localized to the granulosa cells of growing follicles. 17β-estradiol (E2) acting via ERβ augments the actions of follicle stimulating hormone in granulosa cells, leading to granulosa cell differentiation and
Alexandra Zalewski +2 more
doaj +1 more source
Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus [PDF]
BACKGROUND: Current evidence indicates that estrogens, in particular 17β-estradiol (E2), play a crucial role in the gender bias of autoimmune diseases although the underlying molecular mechanisms have not yet been fully elucidated.
ALESSANDRI, cristiano +11 more
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Estrogen, through its receptors, regulates various aspects of spermatogenesis and male fertility. To understand the roles of estrogen receptors (ERα and ERβ) in male fertility, we have developed in vivo selective ER agonist administration models ...
Kushaan Dumasia +3 more
doaj +1 more source
TRIM16 transcription factor in prostate cancer
The aim of this investigation was to reveal the expression TRIM16, ERα, ERβ and AR in prostate cancer tissues compared to benign hyperplasia and clinical and morphological parameters.Materials and methods.
L. V. Spirina +5 more
doaj +1 more source
Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]
Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara +5 more
core +2 more sources
Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha). [PDF]
Matrix metalloproteinases (MMPs) have a crucial function in migration of inflammatory cells into the central nervous system (CNS). Levels of MMP-9 are elevated in multiple sclerosis (MS) and predict the occurrence of new active lesions on magnetic ...
Du, Sienmi +6 more
core +3 more sources
Ecdysteroids: A novel class of anabolic agents? [PDF]
Increasing numbers of dietary supplements with ecdysteroids are marketed as “natural anabolic agents”. Results of recent studies suggested that their anabolic effect is mediated by estrogen receptor (ER) binding. Within this study the anabolic potency of
BOTRE', Francesco +5 more
core +2 more sources
Involvement of sex hormones in colorectal cancer (CRC) development has been linked to oestrogen receptor β (ERβ). Expression of ERβ is found reduced in tumour tissue and inversely related to mortality. However, mechanisms are not well understood.
Sonja Neumeyer +17 more
doaj +1 more source
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease, representing the most aggressive breast cancer (BC) subtype with limited treatment options due to a lack of estrogen receptor alpha (ERα), progesterone receptor (PR), and Erb-B2 ...
Elena Alexandrova +16 more
doaj +1 more source

