Results 211 to 220 of about 225,463 (263)

Perilipin 2 Stabilizes Lipid Droplets and Coordinates Mitochondrial Fatty Acid Flux and ER Stress Adaptation in <i>Apostichopus japonicus</i>. [PDF]

Int J Mol Sci
Fan H, Yu J, Wang W, Lv Z, Zhu S, Li C.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetes. [PDF]

iScience
Rui J, Kothari M, Kursawe R, Barkestani MN, Genosar R, Clark P, Stitzel ML, Herold KC.   +7 more
europepmc   +1 more source

The Impact of REM Sleep Deprivation on ER Stress and Alzheimer-Like Pathology: Therapeutic Potential of Melatonin. [PDF]

Neurochem Res
Çakır A, Şehzade S, Koç C, Çilingir S, Acar D, Süyen G, Bican Demir A, Kahveci N.   +7 more
europepmc   +1 more source

Cypripedin Induces Apoptosis and Synergizes with Bortezomib via ER Stress Mediated Ubiquitination of GRP78 in T-Cell Acute Lymphoblastic Leukemia. [PDF]

Molecules
Ei ZZ, Nutho B, Sritularak B, Chanvorachote P, Chunhacha P.   +4 more
europepmc   +1 more source

Ellagic Acid Attenuates Gentamicin Nephrotoxicity by Integrated Modulation of ER Stress-Associated Apoptosis-Autophagy Crosstalk and Attenuation of Nrf2/HO-1 Signaling. [PDF]

Biomedicines
Salimi A, Khoshnoud MJ, Khodaei Halani F, Jokar S, Bina S, Daneshi SS, Haghshenas M, Rashedinia M.   +7 more
europepmc   +1 more source

Taxane chemotherapy promotes response to TIM-3 checkpoint blockade via STING-mediated ER stress and HMGB1 secretion. [PDF]

Cell Rep Med
Onimus A, Celias D, Chang S, Davis J, Mandula J, Li J, Gardner A, Hänggi K, Osunmakinde O, Soliman H, Shaw TI, Rodriguez PC, Ruffell B.   +12 more
europepmc   +1 more source

The critical role of GRP78/BiP MARylation in ER stress of KRAS-mutant colorectal cancer. [PDF]

JCI Insight
Zhang S, Chen X, Gong Q, Huang J, Tang Y, Xiao M, Li M, Li Q, Wang Y.   +8 more
europepmc   +1 more source

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ER Stress and Autophagy

Current Molecular Medicine, 2015
Eukaryotic cells respond to various types of stresses caused by changes in the extracellular environment. Intracellular factors, such as the accumulation of misfolded proteins in the endoplasmic reticulum (ER), also cause stress and activate the unfolded protein response (UPR), which induces the expression of chaperones and proteins involved in the ...
W-S, Lee, W-H, Yoo, H-J, Chae
openaire   +2 more sources

MicroRNA and ER stress in cancer

Seminars in Cancer Biology, 2021
The development of biological technologies in genomics, proteomics, and bioinformatics has led to the identification and characterization of the complete set of coding genes and their roles in various cellular pathways in cancer. Nevertheless, the cellular pathways have not been fully figured out like a jigsaw puzzle with missing pieces.
Taewan Kim, Carlo M. Croce
openaire   +2 more sources