Results 231 to 240 of about 1,308,915 (353)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Targeting LIPA with ERX-41 Induces ER Stress and Inhibits Tumor Progression in Inflammatory Breast Cancer. [PDF]

Biomolecules
Fuentes Z, Sharma G, Romo BA, Gopalam R, Nassar KM, Ramirez P, Mejia N, Chen CY, Elmore S, Neal H, Nagandla H, Subbarayalu P, Pratap UP, Thomas C, Ahn JM, Raj GV, Viswanadhapalli S, Vadlamudi RK.   +17 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Transient ER stress cell-autonomously promotes beta cell cycling in mice. [PDF]

Diabetologia
Bourgeois S, Van Mulders A, Heremans Y, Leuckx G, Willems L, Coenen S, Degroote L, Pierreux J, Kancheva D, Scheyltjens I, Movahedi K, Carlotti F, de Koning E, Yi X, Vinci C, Tong Y, Cnop M, Heimberg H, De Leu N, Staels W.   +19 more
europepmc   +1 more source

The ER stress related gene panel guide the prognosis and chemosensitivity in acute myeloid leukemia [PDF]

Simei Ren, Hongwei Peng, Luyao Long, Jie Guo, Qi Dai, Li Sun, Lin Yang   +6 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Mitochondrial and ER stress crosstalk in TBI: mechanistic insights and therapeutic opportunities. [PDF]

Front Cell Neurosci
Wenzhe L, Boyang X, Yuchao G, Bimcle R, Yue Y.   +4 more
europepmc   +1 more source

Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung [PDF]

, 2019
Jeryl Sandoval, David J. Orlicky, Ayed Allawzi, Brittany Butler, Cynthia Ju, Caroline T. Phan, Roy J. Toston, Robyn De Dios, Leanna Nguyen, Sarah McKenna, Eva Nozik‐Grayck, Clyde J. Wright   +11 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress. [PDF]

Cell Death Dis
Lin M, Zhang H, Chen S, Zhang J, Tang C, Song X, Zhou J, Xu Z, Mu Y, Zeng H, Yang C, Yu C, Xu C.   +12 more
europepmc   +1 more source