Di-san junyi daxue xuebao, 2020 Objective To screen the genes associated with fluconazole resistance in Trichosporon asahii to facilitate mechanistic studies of fluconazole resistance and the development of new antifungal agents. Methods Three clinical isolates of fluconazole-sensitive
XIA Zhikuan1 +6 more
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Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]
, 2017 This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba +3 more
core +1 more source
Journal of Fungi, 2022 In recent decades, an epidemiological shift has been observed from Candida infections to non-albicans species and resistance to azoles. We investigated the associated factors and molecular mechanisms of azole-resistant blood isolates of C.
Teera Leepattarakit +2 more
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Analysis of the ergosterol biosynthesis pathway cloning, molecular characterization and phylogeny of lanosterol 14α-demethylase (ERG11) gene of Moniliophthora perniciosa [PDF]
Genetics and Molecular Biology, 2014 The phytopathogenic fungus Moniliophthora perniciosa (Stahel) Aime & Philips-Mora, causal agent of witches' broom disease of cocoa, causes countless damage to cocoa production in Brazil.
Geruza de Oliveira Ceita +10 more
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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis. [PDF]
, 2018 BACKGROUND: Cryptococcal meningitis (CM) causes an estimated 180,000 deaths annually, predominantly in sub-Saharan Africa, where most patients receive fluconazole (FLC) monotherapy. While relapse after FLC monotherapy with resistant strains is frequently
Berman, J +13 more
core +6 more sources
Extensive ERG11 mutations associated with fluconazole-resistant Candida albicans isolated from HIV-infected patients [PDF]
Current Medical Mycology, 2019 Background and Purpose: Azoles are preferred antifungal agents given their inexpensiveness, limited toxicity, and potentiality of oral administration.
Sony Paul +2 more
doaj +1 more source
Synthesis of new imidazole-based ionic liquids with antifungal activity against Candida albicans
Iranian Journal of Microbiology, 2023 Background and Objectives: Candida albicans cause a problematic condition in immunocompromised patients that could not be treated quickly due to the resistant behavior of microorganisms. This study aimed to investigate the effect of a novel ionic liquid
Amir Habibi +4 more
doaj +1 more source
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]
, 2019 Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni +6 more
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Investigation of the relationship between fluconazole susceptibility, proteinase activity and ERG11-SAP2 Expression in Candida albicans strains isolated from clinical samples [PDF]
Current Medical MycologyBackground and Purpose: Candida albicans is currently recognised as an opportunistic pathogen that can cause many invasive infections. Resistance mechanisms and fungal virulence factors play an important role in the effectiveness of treatment. The aim of
Nagihan Ege +4 more
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Инфекция и иммунитет, 2022 Candida fungi are common opportunistic microorganisms capable of causing infections of various localization, as well as life-threatening conditions in immunocompromised patients, such as HIV-infected individuals, oncology patients, subjects undergoing ...
A. D. Voropaev +8 more
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