Results 21 to 30 of about 2,525,365 (152)
Revista da Sociedade Brasileira de Medicina Tropical, 2019 INTRODUCTION: Candidiasis is the most frequent opportunistic mycosis in humans and can cause mortality, particularly in immunodeficient patients. One major concern is the increasing number of infections caused by drug-resistant Candidas trains, as these ...
Volmir Pitt Benedetti +6 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Rationale. The low efficacy of azole antimycotics in treatment of Candida infections, especially in HIV-infected patients, is often associated with overexpression of the ERG11 gene in Candida spp., which results in increased production of ergosterol the
Yuri V. Nesvizhsky +7 more
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Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalis.
PLoS ONE, 2022 This study was designed to understand the molecular mechanisms of azole resistance in Candida tropicalis using genetic and bioinformatics approaches. Thirty-two azole-resistant and 10 azole-susceptible (S) clinical isolates of C.
Saikat Paul +6 more
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Analysis of molecular resistance to azole and echinocandin in Candida species in patients with vulvovaginal candidiasis [PDF]
Current Medical Mycology, 2022 Background and Purpose: Vulvovaginal candidiasis (VVC) is considered the most common mucosal infection caused by Candida species. Azoles were considered the firstline treatment for VVC or recurrent vulvovaginal candidiasis (RVVC) in both healthy and ...
Ensieh Lotfali +5 more
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Comparison of ERG11 gene expression profiles of Candida albicans treated with Thymus vulgaris extracts alone and in combination with Mentha spicata [PDF]
Biological Journal of Microorganism, 2018 Introduction:Diseases caused by opportunistic pathogen Candida albicans are usually treated with antifungal drugs, but treatment failure is not uncommon especially in profoundly immunocompromised hosts.
Alireza Khodavandi +2 more
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Antifungal susceptibility and detection of mutant ERG11 gene in vaginal Candida isolates in University of Uyo Teaching Hospital, Uyo, Nigeria [PDF]
, 2020 Background: Candida vulvovaginitis is an important cause of morbidity among women. Fluconazole and other azoles are among the commonest antifungal agents used for the treatment of this condition.
Ikenyi, CL, Atting, IA, Ekuma, AE
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Di-san junyi daxue xuebao, 2020 Objective To screen the genes associated with fluconazole resistance in Trichosporon asahii to facilitate mechanistic studies of fluconazole resistance and the development of new antifungal agents. Methods Three clinical isolates of fluconazole-sensitive
XIA Zhikuan1 +6 more
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Expression of ERG11, ERG3, MDR1 and CDR1 genes in Candida tropicalis
Biomédica: revista del Instituto Nacional de Salud, 2023 Introduction. Drug resistance to azoles is a growing problem in the Candida genus. Objective. To analyze molecularly the genes responsible for fluconazole resistance in Candida tropicalis strains. Materials and methods. Nineteen strains, with and without
Ana Elisa Rojas +3 more
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Recovery Rate of Fungal Pathogens Isolated from Cases of Bovine and Ovine Mycotic Mastitis [PDF]
Journal of Veterinary Medical Research, 2023 Investigating bovine and ovine mycotic mastitis was the study's goal. A total of 250 milk samples were collected from cows, ewes and does suffering from mastitis, not responding for antibiotic therapy, to determine the prevalence of fungal pathogens ...
Ismail Raheel +4 more
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Journal of Fungi, 2022 In recent decades, an epidemiological shift has been observed from Candida infections to non-albicans species and resistance to azoles. We investigated the associated factors and molecular mechanisms of azole-resistant blood isolates of C.
Teera Leepattarakit +2 more
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