Results 1 to 10 of about 511,445 (325)
The effect of high-intensity interval swimming training on CREB and ERK proteins of hippocampus tissue in elderly rats [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2023 Background and Purpose: Cognitive impairment caused by aging has become one of the most common health threats in many countries. Signaling pathways are important moderators of various physiological and pathological processes, and abnormal activation of ...
Zahra Sabri, Mozhgan Ahmadi
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Zhongliu Fangzhi Yanjiu, 2020 Objective To investigate the expression and significance of GPNMB, ERK, MMP3 and MMP9 in primary lesion and bone metastasis of renal cell carcinoma, and to analyze their correlation.
ZHAI Jianpo +4 more
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Frontiers in Bioscience-Landmark, 2023 Background: The mortality rate of colorectal cancer (CRC) ranks second worldwide. Previous research had indicated that licochalcone A (LA) was a flavonoid in licorice with diverse anticancer effects.
Tianpeng Li +11 more
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Redox Report, 2022 Objective Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF ...
Yousra M. El-Far +4 more
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Identification of sphingosine 1-phosphate level and MAPK/ERK signaling in pancreatic β cells [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2021 Purpose Sphingosine kinase is a lipid kinase that phosphorylates sphingosine to generate sphingosine 1-phosphate (S1P). S1P regulates pancreatic islet β-cell endoplasmic reticulum stress and proliferation.
Ji Hyun Park +3 more
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Anti-tumor mechanism of evodiamine on gastric cancer cells in vitro through MAPK signaling pathway
Di-san junyi daxue xuebao, 2021 Objective To investigate the anti-tumor effect of evodiamine on gastric cancer cells via the MAPK signaling pathway. Methods MTT assay was used to assess the cell viability of SGC-7901 cells after the treatment of 8, 16 and 32 μmol/L evocarpine (denoted ...
QIAN Weina +4 more
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Journal of Cell Biology, 2010 In this issue, a study by Groehler and Lannigan (2010. J. Cell Biol. doi:10.1083/jcb.201002124) sheds light on the regulation of proliferating cell nuclear antigen (PCNA) turnover and how it is counteracted by the small chromatin-bound kinase ERK8 (extracellular signal-regulated kinase 8). Importantly, inactivation of ERK8 results in genome instability
Nguyen, Hai Dang, Bielinsky, Anja-Katrin
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The expression of MAPK signaling pathways in conjunctivochalasis [PDF]
International Journal of Ophthalmology, 2019 This study investigated the potential role of MAPK signaling pathways in conjunctivochalasis (CCH). Twenty loose conjunctival biopsy samples from 20 CCH and 15 conjunctival biopsy samples from 15 normal controls (CON) were collected.
Yuan-Ling Jia +4 more
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Di-san junyi daxue xuebao, 2021 Objective To investigate the effects of oncostatin M (OSM) on the proliferation and extracellular matrix secretion of human dermal fibroblasts (HDFs) in high glucose environment and its possible mechanism.
LIU Lulu, FU Xueming, XUE Biyu, XUE Bin
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Molecules, 2020 Osteosarcoma, which is the most prevalent malignant bone tumor, is responsible for the great majority of bone cancer-associated deaths because of its highly metastatic potential. Although tomatidine is suggested to serve as a chemosensitizer in multidrug-
Min-Hong Hsieh +6 more
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